WormBase Tree Display for Gene: WBGene00001214

WBGene00001214 SMap: S_parent: Sequence: F26A3
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: ego
    Allele (67)
    Legacy_information: [Maine EM] ego for Enhancer of Glp-One (glp-1). om18 is recessive enhancer of glp-1(bn18) at 20C, has reduced germ cell number, 50% of wild type in young adult, delayed spermatogenesis, abnormal unfertilized oocytes.
      [C.elegansII] om18 : recessive enhancer of glp-1(bn18) at 20C; has reduced germ cell number, 50% of wild type in young adult, delayed spermatogenesis, abnormal unfertilized oocytes. NA1. [Qiao et al. 1995; EL]
    Strain: WBStrain00040471
      WBStrain00006416
      WBStrain00006425
      WBStrain00006418
      WBStrain00006422
      WBStrain00007147
      WBStrain00007149
      WBStrain00007150
      WBStrain00054544
      WBStrain00055737
    In_cluster: conserved_miRNA_siRNA_cluster
    RNASeq_FPKM (74)
    GO_annotation (23)
    Contained_in_operon: CEOP1412
    Ortholog (56)
    Paralog: WBGene00004510 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004508 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00004509 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: ego-1 encodes a homolog of RNA-directed RNA polymerase; ego-1 is essential for several aspects of germline development such as proliferation, heterochromatin assembly on unpaired DNA during meiosis, and gametogenesis; ego-1 is also required for RNAi in the germ line; EGO-1 is detected in nuclear extracts. Paper_evidence: WBPaper00002279
            WBPaper00004137
            WBPaper00025208
            WBPaper00026940
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 31 Aug 2009 00:00:00
      Automated_description: Predicted to enable RNA-dependent RNA polymerase activity. Involved in gamete generation; nuclear pore localization; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in P granule; condensed nuclear chromosome; and metaphase plate. Expressed in germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F26A3.3
    Corresponding_CDS_history: F26A3.3:wp47
    Corresponding_transcript: F26A3.3.1
    Other_sequence (17)
    Associated_feature: WBsf664469
      WBsf219796
  Experimental_info: RNAi_result (16)
    Expr_pattern (12)
    Drives_construct: WBCnstr00014704
      WBCnstr00019235
      WBCnstr00019236
      WBCnstr00037029
    Construct_product: WBCnstr00014704
      WBCnstr00019236
      WBCnstr00037029
    Antibody: WBAntibody00000957
      WBAntibody00002001
    Microarray_results (15)
    Expression_cluster (130)
    Interaction (37)
    WBProcess: WBbiopr:00000057
  Map_info: Map: I Position: 2.21303 Error: 0.00316
    Well_ordered
    Positive: Positive_clone: F26A3 Person_evidence: WBPerson398
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 3349
        3350
        3351
        3352
        3353
        4644
  Reference: WBPaper00002279
    WBPaper00002972
    WBPaper00003372
    WBPaper00003963
    WBPaper00003990
    WBPaper00004137
    WBPaper00004173
    WBPaper00004301
    WBPaper00004325
    WBPaper00004549
    WBPaper00004563
    WBPaper00004605
    WBPaper00005423
    WBPaper00005601
    WBPaper00005667
    WBPaper00010303
    WBPaper00010532
    WBPaper00010618
    WBPaper00010663
    WBPaper00010706
    WBPaper00010940
    WBPaper00011141
    WBPaper00012007
    WBPaper00015554
    WBPaper00017741
    WBPaper00019495
    WBPaper00022002
    WBPaper00022067
    WBPaper00022521
    WBPaper00023654
    WBPaper00023918
    WBPaper00024202
    WBPaper00024237
    WBPaper00024434
    WBPaper00024516
    WBPaper00024826
    WBPaper00025208
    WBPaper00025632
    WBPaper00025676
    WBPaper00025795
    WBPaper00026021
    WBPaper00026344
    WBPaper00026940
    WBPaper00027253
    WBPaper00027259
    WBPaper00027261
    WBPaper00027276
    WBPaper00027781
    WBPaper00028417
    WBPaper00031487
    WBPaper00031961
    WBPaper00031962
    WBPaper00034962
    WBPaper00035228
    WBPaper00035245
    WBPaper00035269
    WBPaper00035324
    WBPaper00035499
    WBPaper00035534
    WBPaper00035889
    WBPaper00035898
    WBPaper00036918
    WBPaper00038226
    WBPaper00038491
    WBPaper00040600
    WBPaper00040602
    WBPaper00041373
    WBPaper00041827
    WBPaper00043989
    WBPaper00045091
    WBPaper00046160
    WBPaper00047234
    WBPaper00048203
    WBPaper00048225
    WBPaper00048493
    WBPaper00050743
    WBPaper00052481
    WBPaper00056901
    WBPaper00057161
    WBPaper00058600
    WBPaper00060343
    WBPaper00060750
    WBPaper00061137
    WBPaper00061484
    WBPaper00061881
    WBPaper00063551
    WBPaper00065293
  Remark: data extracted from letter, WBG 13-4:41.
  Method: Gene