WormBase Tree Display for Gene: WBGene00010988
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WBGene00010988 | SMap | S_parent | Sequence | R03D7 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | metr | |||||
Allele (55) | ||||||
Strain | WBStrain00001842 | |||||
WBStrain00002165 | ||||||
WBStrain00031469 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00054834 | |||||
00054835 | ||||||
00054836 | ||||||
00054837 | ||||||
00054838 | ||||||
00054839 | ||||||
00054840 | ||||||
00054841 | ||||||
00054842 | ||||||
00054843 | ||||||
00054844 | ||||||
00054845 | ||||||
00054846 | ||||||
00054847 | ||||||
00054848 | ||||||
00054849 | ||||||
00118287 | ||||||
00118288 | ||||||
00118289 | ||||||
00118290 | ||||||
00118291 | ||||||
00118292 | ||||||
00118293 | ||||||
Ortholog (39) | ||||||
Paralog | WBGene00015512 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||
WBGene00020491 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | metr-1 encodes a protein orthologous to the human gene Methionine synthase (MTR), which is involved in the conversion of homocysteine to form methionine. | Paper_evidence | WBPaper00042203 | ||
Curator_confirmed | WBPerson324 | |||||
WBPerson1823 | ||||||
WBPerson567 | ||||||
Date_last_updated | 07 May 2013 00:00:00 | |||||
Automated_description | Predicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Experimental_model | DOID:9352 | Homo sapiens | Paper_evidence | WBPaper00042203 | |
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 13 Mar 2023 00:00:00 | |||||
Potential_model (14) | ||||||
Models_disease_asserted | WBDOannot00000175 | |||||
Molecular_info | Corresponding_CDS | R03D7.1 | ||||
Corresponding_transcript | R03D7.1.1 | |||||
Other_sequence (51) | ||||||
Associated_feature | WBsf222084 | |||||
WBsf222085 | ||||||
Experimental_info | RNAi_result | WBRNAi00071221 | Inferred_automatically | RNAi_primary | ||
WBRNAi00034551 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00090587 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00051170 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00106971 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00017346 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Chronogram417 | |||||
Chronogram1093 | ||||||
Expr6447 | ||||||
Expr6448 | ||||||
Expr1028258 | ||||||
Expr1034818 | ||||||
Expr1154877 | ||||||
Expr2013538 | ||||||
Expr2031772 | ||||||
Drives_construct | WBCnstr00002636 | |||||
WBCnstr00004383 | ||||||
Regulate_expr_cluster | WBPaper00060951:metr-1(os521)_downregulated | |||||
WBPaper00060951:metr-1(os521)_upregulated | ||||||
Microarray_results (20) | ||||||
Expression_cluster (213) | ||||||
Interaction (110) | ||||||
Map_info (3) | ||||||
Reference (25) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |