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WormBase Tree Display for Gene: WBGene00003864

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Name Class

WBGene00003864SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion1
NameCGC_nameoma-1Person_evidenceWBPerson374
Sequence_nameC09G9.6
Molecular_nameC09G9.6
C09G9.6.1
CE03005
Other_namemoe-1
CELE_C09G9.6Accession_evidenceNDBBX284604
Public_nameoma-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classoma
Allele (56)
StrainWBStrain00035069
WBStrain00035066
WBStrain00035067
WBStrain00035068
WBStrain00040433
WBStrain00040434
WBStrain00048324
WBStrain00052677
RNASeq_FPKM (74)
GO_annotation00011265
00011266
00011267
00011268
00011269
00011270
00011271
00011272
00011273
00011274
00011275
00011276
00011277
00011278
00011279
00011280
00011281
00011282
00011283
00011284
00011285
00011286
00011287
00011288
00011289
00011290
00011291
00011292
00011293
00011294
00011295
00011296
00011297
00011298
00011299
00011300
00011301
00011302
00011303
00011304
00011305
00011306
00011307
00011308
00011309
00011310
00011311
00011312
00011313
00011314
00011315
00011316
00011317
00111930
00111931
Contained_in_operonCEOP4312
Ortholog (51)
Paralog (20)
Structured_descriptionConcise_descriptionoma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization.Paper_evidenceWBPaper00005198
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated19 Mar 2012 00:00:00
Automated_descriptionEnables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0014769Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1108)
Molecular_infoCorresponding_CDSC09G9.6
Corresponding_transcriptC09G9.6.1
Other_sequenceXIC01512_1
HG11531
XI03775
SRC08713_1
FC813056.1
Associated_feature (15)
Gene_product_bindsWBsf034245
Transcription_factorWBTranscriptionFactor000116
Experimental_infoRNAi_result (29)
Expr_pattern (16)
Drives_construct (13)
Construct_product (14)
AntibodyWBAntibody00000486
WBAntibody00000547
WBAntibody00001073
WBAntibody00001074
WBAntibody00001087
WBAntibody00001664
WBAntibody00002447
Microarray_results (20)
Expression_cluster (207)
Interaction (354)
WBProcessWBbiopr:00000068
WBbiopr:00000073
Map_infoMapIVPosition3.99916Error0.001096
PositivePositive_cloneC09G9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data (2)
Reference (94)
PictureWBPicture0000013094
RemarkWeak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1]
Sequence connection based on Lin, R [021017 ck1]
Sequence connection from [Shimada M], [krb 020711]
Postitive method is weak rescue of the zu405 embryonic lethality
MethodGene