WormBase Tree Display for Gene: WBGene00018783
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WBGene00018783 | SMap | S_parent | Sequence | F54A3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cbs-2 | Paper_evidence | WBPaper00039977 | |||||
Person_evidence | WBPerson537 | ||||||||
Sequence_name | F54A3.4 | ||||||||
Molecular_name | F54A3.4 | ||||||||
F54A3.4.1 | |||||||||
CE47819 | |||||||||
Other_name | F54A3.d | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
F54A3.e | Curator_confirmed | WBPerson1983 | |||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_F54A3.4 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | cbs-2 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 29 Sep 2011 10:45:56 | WBPerson2970 | Name_change | CGC_name | cbs-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cbs | ||||||||
Allele (177) | |||||||||
Strain | WBStrain00031552 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00094692 | ||||||||
00094693 | |||||||||
00094694 | |||||||||
00094695 | |||||||||
00094696 | |||||||||
00094697 | |||||||||
00094698 | |||||||||
00094699 | |||||||||
00094700 | |||||||||
00094701 | |||||||||
00094702 | |||||||||
Contained_in_operon | CEOP2708 | ||||||||
Ortholog (23) | |||||||||
Paralog | WBGene00007653 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00008490 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00008732 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00010759 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00013866 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00019096 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00019962 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00019094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00020797 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00010456 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00011353 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00021787 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | The F54A3.4 gene encodes a homolog of the human gene CBS, which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable cystathionine beta-synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
Molecular_info | Corresponding_CDS | F54A3.4 | |||||||
Corresponding_CDS_history | F54A3.4:wp233 | ||||||||
Corresponding_transcript | F54A3.4.1 | ||||||||
Other_sequence (18) | |||||||||
Experimental_info | RNAi_result | WBRNAi00048206 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00015558 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048207 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015557 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1026794 | ||||||||
Expr1038097 | |||||||||
Expr1152016 | |||||||||
Expr2009745 | |||||||||
Expr2027985 | |||||||||
Microarray_results (12) | |||||||||
Expression_cluster (167) | |||||||||
Interaction (85) | |||||||||
Map_info | Map | II | Position | -13.8397 | Error | 0.00061 | |||
Positive | Positive_clone | F54A3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00038491 | ||||||||
WBPaper00039977 | |||||||||
WBPaper00040475 | |||||||||
WBPaper00040626 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00059856 | |||||||||
WBPaper00060693 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |