WormBase Tree Display for Gene: WBGene00021508

WBGene00021508 SMap: S_parent: Sequence: Y41D4A
  Identity: Version: 1
    Name (4)
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (108)
    RNASeq_FPKM (74)
    GO_annotation (21)
    Ortholog (43)
    Paralog: WBGene00012750 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013164 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013226 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013232 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015047 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015048 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019068 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Is an ortholog of human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112117 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21020)
  Molecular_info: Corresponding_CDS: Y41D4A.6a
      Y41D4A.6b
      Y41D4A.6c
      Y41D4A.6d
      Y41D4A.6e
      Y41D4A.6f
    Corresponding_transcript: Y41D4A.6a.1
      Y41D4A.6b.1
      Y41D4A.6c.1
      Y41D4A.6d.1
      Y41D4A.6e.1
      Y41D4A.6f.1
    Other_sequence (20)
    Associated_feature: WBsf651653
      WBsf995519
      WBsf995520
      WBsf1016779
      WBsf229781
  Experimental_info: RNAi_result: WBRNAi00024150 Inferred_automatically: RNAi_primary
      WBRNAi00056373 Inferred_automatically: RNAi_primary
      WBRNAi00023350 Inferred_automatically: RNAi_primary
      WBRNAi00020477 Inferred_automatically: RNAi_primary
      WBRNAi00023863 Inferred_automatically: RNAi_primary
      WBRNAi00024223 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1012872
      Expr1039400
      Expr1159860
      Expr2007439
      Expr2025675
    Microarray_results (27)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045729:gld-4(RNAi)_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053039:Aspirin_upregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061340:Rectal_cell
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:mtr-4_1623-W03F9.10_103
      WBPaper00061527:trcs-2_5724-R11A8.7_17645
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00064735:bet-1B(OE)mys-1(RNAi)_vs_mys-1(RNAi)_upregulated
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      cgc4489_group_14
      WBPaper00025032:cluster_31
      WBPaper00025032:cluster_171
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_H
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:male_sex-enriched
    Interaction (14)
  Map_info: Positive: Positive_clone: Y41D4A Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV -16.0759
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene