WormBase Tree Display for Gene: WBGene00015047
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| WBGene00015047 | SMap | S_parent | Sequence | B0218 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | faah-1 | Person_evidence | WBPerson3660 | |||||
| WBPerson3406 | |||||||||
| WBPerson1799 | |||||||||
| Sequence_name | B0218.1 | ||||||||
| Molecular_name | B0218.1 | ||||||||
| B0218.1.1 | |||||||||
| CE06684 | |||||||||
| B0218.1.2 | |||||||||
| B0218.1.3 | |||||||||
| Other_name | svh-3 | Paper_evidence | |||||||
| Person_evidence | WBPerson1068 | ||||||||
| WBPerson1315 | |||||||||
| CELE_B0218.1 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | faah-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 21 Apr 2009 16:04:55 | WBPerson9133 | Name_change | CGC_name | faah-1 | ||||
| 3 | 04 Apr 2017 12:10:45 | WBPerson2970 | Name_change | Other_name | svh-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | faah | ||||||||
| Allele (37) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00058193 | ||||||||
| 00058194 | |||||||||
| 00058195 | |||||||||
| 00058196 | |||||||||
| 00058197 | |||||||||
| 00058198 | |||||||||
| 00058199 | |||||||||
| 00058200 | |||||||||
| 00058201 | |||||||||
| 00058202 | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00012750 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00013226 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013232 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00015048 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00019068 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013164 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021508 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | faah-1 encodes a putative fatty acid amide hydrolase enzyme and is orthologous to human fatty acid amide hydrolase (FAAH); faah-1 is involved in regulating N-acylethanolamines (NAEs), which are lipid-derived signalling molecules, reduced levels of which, under dietary restriction, result in increased lifespan; faah-1 functions to hydrolyse N-acylethanolamines (NAEs) like eicosapentaenoyl ethanolamide (EPEA) and arachidonoyl ethanolamide (AEA), as worms overexpressing faah-1 had reduced levels of NAEs; faah-1 is also required for normal growth and development. | Paper_evidence | WBPaper00041646 | |||||
| WBPaper00038417 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 02 Apr 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable amidase activity and fatty acid amide hydrolase activity. Involved in positive regulation of axon regeneration. Expressed in pharyngeal neurons and pharynx. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:303 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3553) | ||||
| DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3553) | ||||||
| Molecular_info | Corresponding_CDS | B0218.1 | |||||||
| Corresponding_CDS_history | B0218.1b:wp261 | ||||||||
| Corresponding_transcript | B0218.1.1 | ||||||||
| B0218.1.2 | |||||||||
| B0218.1.3 | |||||||||
| Other_sequence (44) | |||||||||
| Associated_feature | WBsf228636 | ||||||||
| WBsf228637 | |||||||||
| WBsf228638 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027997 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00009591 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001800 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038743 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9301 | ||||||||
| Expr10655 | |||||||||
| Expr13911 | |||||||||
| Expr1021051 | |||||||||
| Expr1036428 | |||||||||
| Expr1142954 | |||||||||
| Expr2011412 | |||||||||
| Expr2029648 | |||||||||
| Drives_construct | WBCnstr00008603 | ||||||||
| WBCnstr00013885 | |||||||||
| WBCnstr00017426 | |||||||||
| WBCnstr00029130 | |||||||||
| Construct_product | WBCnstr00008294 | ||||||||
| WBCnstr00008295 | |||||||||
| WBCnstr00008604 | |||||||||
| WBCnstr00008605 | |||||||||
| WBCnstr00008606 | |||||||||
| WBCnstr00029130 | |||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (187) | |||||||||
| Interaction (120) | |||||||||
| Map_info | Map | IV | Position | 3.64664 | Error | 0.000578 | |||
| Positive | Positive_clone | B0218 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00041646 | |||||||||
| WBPaper00043050 | |||||||||
| WBPaper00043348 | |||||||||
| WBPaper00046049 | |||||||||
| WBPaper00047621 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060352 | |||||||||
| WBPaper00065026 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
