WormBase Tree Display for Gene: WBGene00019767

WBGene00019767 SMap: S_parent: Sequence: M04F3
  Identity: Version: 2
    Name: CGC_name: rpa-2
      Sequence_name: M04F3.1
      Molecular_name: M04F3.1
        M04F3.1.1
        CE12414
      Other_name: CeRPA Paper_evidence: WBPaper00025014
            WBPaper00031956
        CeRPA32 Paper_evidence: WBPaper00040684
        CELE_M04F3.1 Accession_evidence: NDB BX284601
      Public_name: rpa-2
    DB_info: Database: AceView gene 1F339
        WormQTL gene WBGene00019767
        WormFlux gene WBGene00019767
        NDB locus_tag CELE_M04F3.1
        Panther gene CAEEL|WormBase=WBGene00019767|UniProtKB=Q95Y97
          family PTHR13989
        NCBI gene 172092
        RefSeq protein NM_059045.8
        TREEFAM TREEFAM_ID TF352968
        TrEMBL UniProtAcc Q95Y97
        UniProt_GCRP UniProtAcc Q95Y97
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 07 Feb 2007 08:58:58 WBPerson2970 Name_change: CGC_name: rpa-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rpa
    Allele (14)
    Strain: WBStrain00035259
      WBStrain00036377
      WBStrain00034799
      WBStrain00051041
      WBStrain00051036
      WBStrain00051034
      WBStrain00051035
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog (22)
    Paralog: WBGene00019079 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: rpa-2 encodes the C. elegans homolog of the medium subunit of replication protein A (RPA); by homology RPA-2 is predicted to function in several DNA metabolic processes, including recombination, repair, and replication, as well as cell cycle and DNA damage checkpoints; RPA-2 physically interacts with RPA-1, the RPA large subunit, in vivo. Paper_evidence: WBPaper00025138
          Curator_confirmed: WBPerson1843
          Date_last_updated: 05 Aug 2012 00:00:00
      Automated_description: Enables enzyme binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. Expressed in pharyngeal neurons and seam cell. Is an ortholog of human RPA2 (replication protein A2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: M04F3.1
    Corresponding_transcript: M04F3.1.1
    Other_sequence: CGC00518_1
      CRC01239_1
      CR09300
      CR09179
      CBC03124_1
      CJC02916_1
      CR02657
    Associated_feature (8)
  Experimental_info: RNAi_result (18)
    Expr_pattern: Chronogram2029
      Expr7623
      Expr1026249
      Expr1038551
      Expr1154609
      Expr1200320
      Expr2015415
      Expr2033650
    Drives_construct: WBCnstr00001067
      WBCnstr00012768
      WBCnstr00025609
    Construct_product: WBCnstr00025609
    Microarray_results (21)
    Expression_cluster: WBPaper00027057:DCR-1_interacting_embryo
      WBPaper00028360:Phospho-Sulfo-Modified_proteins
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00038289:oocyte_protein
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00040420:ALM_PLM_enriched
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044760:germline_specific
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049626:UNC-75_target
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051311:VGLN-1-interacting
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00054792:FOG-3_interacting
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059194:KLF-1_interacting
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:ABarpaaa_lineage
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:lst-3_9016-W03F9.10_13548
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_upregulated_body-wall-muscle
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064315:mes-4(bn73)_downregulated_PGCs
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064716:paraquat_upregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_6_2
      cgc4489_group_3
      WBPaper00025032:cluster_32
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00051448:P.aeruginosa_Slow-Killing_upregulated
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(101_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:intrinsic
    Interaction (266)
  Map_info: Map: I Position: -0.738345 Error: 0.002057
    Positive: Positive_clone: M04F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (14)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene