WormBase Tree Display for Gene: WBGene00017483

WBGene00017483 SMap: S_parent: Sequence: F15E6
  Identity: Version: 2
    Name: CGC_name: lgc-22 Paper_evidence: WBPaper00029376
          Person_evidence: WBPerson1430
      Sequence_name: F15E6.2
      Molecular_name: F15E6.2a
        F15E6.2a.1
        CE36293
        F15E6.2b
        CE16991
        F15E6.2b.1
      Other_name: CELE_F15E6.2 Accession_evidence: NDB BX284604
      Public_name: lgc-22
    DB_info: Database: AceView gene 4F67
        WormQTL gene WBGene00017483
        WormFlux gene WBGene00017483
        NDB locus_tag CELE_F15E6.2
        NCBI gene 184533
        RefSeq protein NM_001268330.3
            NM_001268331.5
        TrEMBL UniProtAcc O44497
            I2HA93
        UniProt_GCRP UniProtAcc O44497
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 May 2007 16:58:23 WBPerson2970 Name_change: CGC_name: lgc-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lgc
    Allele (60)
    Strain: WBStrain00055270
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (27)
    Paralog (107)
    Structured_description: Automated_description: Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F15E6.2a
      F15E6.2b
    Corresponding_CDS_history: F15E6.2:wp114
    Corresponding_transcript: F15E6.2a.1
      F15E6.2b.1
    Other_sequence (16)
    Associated_feature: WBsf645914
      WBsf655017
      WBsf660092
      WBsf228183
  Experimental_info: RNAi_result (3)
    Expr_pattern: Expr1012985
      Expr1037520
      Expr1148708
      Expr1200311
      Expr2013101
      Expr2031333
    Drives_construct: WBCnstr00027263
    Construct_product: WBCnstr00027263
    Microarray_results (20)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00041954:ethanol_upregulated
      WBPaper00042561:smgl-2(RNAi)_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00044246:pgrn-1_ced-3_ced-1_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045316:prg-1_downregulated_L1
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050709:jmjd-1.2(tm3713)_regulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00051461:pig-1(gm344)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:efa-6(tm3124)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_L2
      WBPaper00056218:daf-16(mu86)_upregulated_Day3
      WBPaper00056284:ints-1(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058927:high-redox-state_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Hypodermis
      WBPaper00061340:Tail_hypodermis
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:saeg-1_18803-mpz-2_15880
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062715:blmp-1(s71)_upregulated
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064871:hypoxia_downregulated_F2
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:33_1
      WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_4_6
      cgc4489_group_8
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_E
      WBPaper00029437:dcr-1_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:FedUp
      WBPaper00032948:MoltOssilate
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:aak-2overexpression_down_regulated
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040185:nhr-23(RNAi)_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040876:mir-35_downregulated
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00044535:male_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_B
    Interaction (184)
  Map_info: Map: IV Position: 0.143729
    Positive: Positive_clone: F15E6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene