WormBase Tree Display for Gene: WBGene00016167

WBGene00016167 SMap: S_parent: Sequence: C27F2
  Identity: Version: 2
    Name: CGC_name: vps-22 Person_evidence: WBPerson3188
      Sequence_name: C27F2.5
      Molecular_name: C27F2.5
        C27F2.5.1
        CE26875
        C27F2.5.2
      Other_name: CELE_C27F2.5 Accession_evidence: NDB BX284603
      Public_name: vps-22
    DB_info: Database: AceView gene 3G52+3G50
            3G50
        WormQTL gene WBGene00016167
        WormFlux gene WBGene00016167
        NDB locus_tag CELE_C27F2.5
        Panther gene CAEEL|WormBase=WBGene00016167|UniProtKB=Q18258
          family PTHR12806
        NCBI gene 175672
        RefSeq protein NM_065651.8
        TREEFAM TREEFAM_ID TF105950
        TrEMBL UniProtAcc Q18258
        UniProt_GCRP UniProtAcc Q18258
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 26 Feb 2009 16:18:19 WBPerson2970 Name_change: CGC_name: vps-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: vps
    Allele (30)
    RNASeq_FPKM (74)
    GO_annotation: 00060797
      00060798
      00060799
      00060800
      00060801
      00121861
      00121862
    Contained_in_operon: CEOP3248
    Ortholog (32)
    Structured_description: Concise_description: C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport. Paper_evidence: WBPaper00026641
          Curator_confirmed: WBPerson1843
          Date_last_updated: 31 Jul 2007 00:00:00
      Automated_description: Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT II complex. Expressed in body wall musculature; pharyngeal muscle cell; pharynx; and vulval muscle. Is an ortholog of human SNF8 (SNF8 subunit of ESCRT-II). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C27F2.5
    Corresponding_CDS_history: C27F2.5a:wp135
      C27F2.5b:wp135
    Corresponding_transcript: C27F2.5.1
      C27F2.5.2
    Other_sequence (54)
    Associated_feature: WBsf651025
      WBsf226616
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr12774
      Expr12778
      Expr15896
      Expr1013359
      Expr1036920
      Expr1145400
      Expr2018014
      Expr2036151
    Drives_construct: WBCnstr00022878
      WBCnstr00028279
      WBCnstr00042586
    Construct_product: WBCnstr00022878
      WBCnstr00028279
      WBCnstr00042586
    Microarray_results (34)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059763:neuron_expressed
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061527:trm-1-H43I07.2
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064716:paraquat_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00025032:cluster_147
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:StarveUp4
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037611:GLD-2-associated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_A
    Interaction (48)
  Map_info: Map: III Position: -2.30024 Error: 0.00462
    Positive: Positive_clone: C27F2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (7)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene