WormBase Tree Display for Gene: WBGene00012231

WBGene00012231 SMap: S_parent: Sequence: W04A4
  Identity: Version: 1
    Name: Sequence_name: W04A4.2
      Molecular_name: W04A4.2
        W04A4.2.1
        CE42178
      Other_name: CELE_W04A4.2 Accession_evidence: NDB BX284601
      Public_name: W04A4.2
    DB_info: Database: AceView gene 1O275
        WormQTL gene WBGene00012231
        WormFlux gene WBGene00012231
        NDB locus_tag CELE_W04A4.2
        NCBI gene 189178
        RefSeq protein NM_060998.4
        TrEMBL UniProtAcc O45888
        UniProt_GCRP UniProtAcc O45888
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (31)
    RNASeq_FPKM (74)
    Ortholog: WBGene00142228 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00063773 Caenorhabditis remanei From_analysis: Inparanoid_8
      WBGene00063531 Caenorhabditis remanei From_analysis: Inparanoid_8
      chrI_pilon.g2775 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Enriched in several structures, including ADL; DVA; germ line; gonadal sheath cell; and interfacial epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq and microarray studies. Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W04A4.2
    Corresponding_CDS_history: W04A4.2:wp127
      W04A4.2:wp187
    Corresponding_transcript: W04A4.2.1
    Associated_feature: WBsf218755
  Experimental_info: RNAi_result: WBRNAi00054739 Inferred_automatically: RNAi_primary
      WBRNAi00004408 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013496
      Expr1158276
      Expr2006751
      Expr2024971
    Microarray_results (15)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00042215:wdr-23(tm1817)_downregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044037:eat-2_downregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00045521:Spermatogenic
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:ash-2(tm1095)_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00047131:daf-2(e1370)_downregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_upregulated
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049920:hyl-2(tm2031)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)_vs_control_L4
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:15C_upregulated_OP50
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056039:ptl-1(ok621)_upregulated
      WBPaper00056039:ptrn-1(tm5597)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_upregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059477:hlh-2(RNAi)_regulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060273:vrk-1(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060911:prx-5(RNAi)_downregulated_mRNA
      WBPaper00061081:E.faecalis_downregulated_skpo-1(ok1640)
      WBPaper00061340:ADL
      WBPaper00061340:B
      WBPaper00061340:DVA
      WBPaper00061340:F_U
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061527:ZC373.2-Y62H9A.6_1596
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061952:daf-18(yh1)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062590:Aging_downregulated_body-wall-muscle
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062672:dcp-66(RNAi)_downregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064156:lipl-4(overexpress)_downregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064661:lpd-3(ok2138)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064788:ketamine_downregulated
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065841:3_0
      WBPaper00065841:18_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_11
      WBPaper00026980:intestine_enriched
      WBPaper00027111:rde-3(r459)_downregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00040963:Q200_down
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050515:nipi-3(fr4)_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc6390]:Cluster_C
    Interaction: WBInteraction000406719
  Map_info: Positive: Positive_clone: W04A4 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 21.6388
  Method: Gene