WormBase Tree Display for Gene: WBGene00010539

WBGene00010539 SMap: S_parent: Sequence: K03H1
  Identity: Version: 2
    Name: CGC_name: ttr-2
      Sequence_name: K03H1.4
      Molecular_name: K03H1.4
        K03H1.4.1
        CE00475
      Other_name: CELE_K03H1.4 Accession_evidence: NDB BX284603
      Public_name: ttr-2
    DB_info: Database: AceView gene 3L17
        WormQTL gene WBGene00010539
        WormFlux gene WBGene00010539
        NDB locus_tag CELE_K03H1.4
        Panther gene CAEEL|WormBase=WBGene00010539|UniProtKB=P34500
          family PTHR21700
        NCBI gene 176403
        RefSeq protein NM_066802.7
        SwissProt UniProtAcc P34500
        TREEFAM TREEFAM_ID TF315773
        UniProt_GCRP UniProtAcc P34500
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Sep 2007 11:48:01 WBPerson2970 Name_change: CGC_name: ttr-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ttr
    Allele (21)
    RNASeq_FPKM (74)
    GO_annotation: 00042703
      00042704
      00117898
    Ortholog (23)
    Paralog (62)
    Structured_description: Concise_description: K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known. Paper_evidence: WBPaper00002969
          Curator_confirmed: WBPerson1843
          Date_last_updated: 04 Sep 2007 00:00:00
      Automated_description: Predicted to be located in cell surface and extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info (4)
  Experimental_info: RNAi_result: WBRNAi00049853 Inferred_automatically: RNAi_primary
      WBRNAi00006712 Inferred_automatically: RNAi_primary
      WBRNAi00046853 Inferred_automatically: RNAi_primary
      WBRNAi00016553 Inferred_automatically: RNAi_primary
      WBRNAi00033427 Inferred_automatically: RNAi_primary
      WBRNAi00000310 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram894
      Chronogram1301
      Chronogram1517
      Expr1012016
      Expr1034597
      Expr1153561
      Expr2017595
      Expr2035734
    Drives_construct: WBCnstr00031343
    Construct_product: WBCnstr00031343
    Microarray_results (19)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00028451:Oogenic_protein
      WBPaper00029359_1280
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1604
      WBPaper00030922:glycosylated_protein
      WBPaper00031040:Cluster_3
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:down_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038213:E.coli(LF82)_72h_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00040446:insoluble_protein
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046217:gas-1(fc21)_upregulated
      WBPaper00046217:mev-1(kn1)_upregulated
      WBPaper00046446:rapid-synthesized_YoungAdult
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048980:aging_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050053:muscle_enriched_Day12
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050698:DEP-1_interacting
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:vulva-uterus_expressed
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00055981:fog-2(q71)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L3
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:iff-1(RNAi)_upregulated_protein
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058927:high-redox-state_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-extract_12h_regulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:Anterior_arcade_cell
      WBPaper00061340:Coelomocyte
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:Hypodermis
      WBPaper00061340:P_cell
      WBPaper00061340:Rectal_gland
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061479:hrde-1(tm1200)_upregulated
      WBPaper00061527:W01F3.2_1554-Y106G6D.8
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064156:lbp-3(overexpress)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064735:bet-1(RNAi)_vs_N2_upregulated
      WBPaper00064735:bet-1(uth41)_vs_N2_upregulated
      WBPaper00064841:tent-5(tm3504)_downregulated_transcript
      WBPaper00064850:glh-1(sam65)_upregulated
      WBPaper00064952:Day5_vs_L4_upregulated_25C
      WBPaper00064952:Day10_vs_Day1_upregulated_20C
      WBPaper00064952:Day10_vs_Day1_upregulated_25C
      WBPaper00064952:Day10_vs_Day5_upregulated_25C
      WBPaper00064952:Day10_vs_L4_upregulated_20C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065623:48
      WBPaper00065623:60
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:11_1
      WBPaper00065841:11_3
      WBPaper00065841:43_0
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      cgc4386_cluster_2_2
      cgc4489_group_9
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00030985:Serratia_marcesens_downregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00036286:Pattern_F
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc6390]:Cluster_A
    Interaction (171)
  Map_info: Map: III Position: 1.23456 Error: 0.012844
    Positive: Positive_clone: K03H1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (2)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene