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WormBase Tree Display for Gene: WBGene00010403

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Name Class

WBGene00010403SMapS_parentSequenceCHROMOSOME_X
IdentityVersion2
NameCGC_nameotpl-8
Sequence_nameH19J13.1
Molecular_nameH19J13.1
H19J13.1.1
CE51331
Other_nameCELE_H19J13.1Accession_evidenceNDBBX284606
Public_nameotpl-8
DB_infoDatabaseAceViewgeneXM884
WormQTLgeneWBGene00010403
WormFluxgeneWBGene00010403
NDBlocus_tagCELE_H19J13.1
PanthergeneCAEEL|WormBase=WBGene00010403|UniProtKB=G5EDX5
familyPTHR21522
NCBIgene186752
RefSeqproteinNM_077644.6
TREEFAMTREEFAM_IDTF313428
TrEMBLUniProtAccG5EDX5
UniProt_GCRPUniProtAccG5EDX5
SpeciesCaenorhabditis elegans
HistoryVersion_change (2)
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classotpl
Allele (65)
StrainWBStrain00050999
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (45)
ParalogWBGene00017034Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00018478Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018479Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018480Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00015035Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017449Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018477Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionotpl-8 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-8 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-8's paralogs include OTPL-1 through OTPL-7; OTPL-8 has no function in mass RNAi assays.Paper_evidenceWBPaper00031620
WBPaper00031621
WBPaper00031622
WBPaper00031623
Curator_confirmedWBPerson567
Date_last_updated04 Apr 2008 00:00:00
Automated_descriptionPredicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSH19J13.1
Corresponding_CDS_historyH19J13.1:wp252
Corresponding_transcriptH19J13.1.1
Other_sequenceBM01130
Associated_featureWBsf1007263
WBsf1007264
WBsf238053
Experimental_infoRNAi_resultWBRNAi00033722Inferred_automaticallyRNAi_primary
WBRNAi00016278Inferred_automaticallyRNAi_primary
WBRNAi00049429Inferred_automaticallyRNAi_primary
Expr_patternExpr1025873
Expr1153157
Expr2014664
Expr2032897
Drives_constructWBCnstr00031440
Construct_productWBCnstr00031440
Microarray_results (16)
Expression_clusterWBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00044037:eat-2_upregulated
WBPaper00044260:1-methylnicotinamide_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044760:somatic_specific
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00046024:sleep_upregulated_oscillating
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00055013:hmg-3(bar24)_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_L2
WBPaper00056284:ints-1(RNAi)_downregulated
WBPaper00056290:mdt-15(mg584)_downregulated
WBPaper00056330:glycine_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056617:adr-1_upregulated_embryo_transcript
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060909:atfs-1(et18)_downregulated
WBPaper00060921:tph-1(mg280)_upregulated
WBPaper00061040:eat-2(ad1116)_upregulated
WBPaper00061340:Arcade_cell_anterior_and_posterior
WBPaper00061340:RID_parent
WBPaper00061424:Diet_MYb120_upregulated
WBPaper00061527:C54G4.4-Y45F3A.8
WBPaper00061753:csr-1(tor159)_upregulated_20C
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062156:jmjd-1.2(zr1010)_upregulated
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062456:doxycycline_upregulated_N2_transcript
WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064494:postdauer_downregulated_WholeAnimal
WBPaper00064532:pals-25(icb98)_upregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065746:eat-2(ad1113)_downregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
cgc4489_group_22
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00034739:N2lessDR1350
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:N2_starvation_downregulated
InteractionWBInteraction000153287
WBInteraction000413423
Map_infoMapXPosition7.0159
PositivePositive_cloneH19J13Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031620
WBPaper00031622
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene