WormBase Tree Display for Gene: WBGene00010063

WBGene00010063 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: dhrs-4 Paper_evidence: WBPaper00042191
      Sequence_name: F54F3.4
      Molecular_name: F54F3.4
        F54F3.4.1
        CE19894
      Other_name: Q93790 Paper_evidence: WBPaper00038108
        NP_506230 Paper_evidence: WBPaper00042191
        CELE_F54F3.4 Accession_evidence: NDB BX284605
      Public_name: dhrs-4
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dhrs
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation: 00019834
      00019835
      00019836
      00019837
      00019838
      00019839
    Ortholog (39)
    Paralog (22)
    Structured_description: Concise_description: dhrs-4 encodes a member of the short-chain dehydrogenase/reductase (SDR) family; by orthology to human DHRS4, C. elegans DHRS-4 is predicted to function as a tetrameric, peroxisomal NADPH-dependent carbonyl-reductase that acts on a large and diverse set of small molecule substrates. Paper_evidence: WBPaper00042191
          Curator_confirmed: WBPerson1843
          Date_last_updated: 15 Apr 2013 00:00:00
      Automated_description: Enables carbonyl reductase (NADPH) activity. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F54F3.4
    Corresponding_transcript: F54F3.4.1
    Other_sequence (60)
    Associated_feature: WBsf647419
      WBsf661944
      WBsf1001668
      WBsf1020627
      WBsf232715
  Experimental_info: RNAi_result: WBRNAi00032815 Inferred_automatically: RNAi_primary
      WBRNAi00048377 Inferred_automatically: RNAi_primary
      WBRNAi00015657 Inferred_automatically: RNAi_primary
      WBRNAi00092606 Inferred_automatically: RNAi_primary
      WBRNAi00007346 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026386
      Expr1034391
      Expr1152166
      Expr2010893
      Expr2029132
    Drives_construct: WBCnstr00031697
    Construct_product: WBCnstr00031697
    Microarray_results (18)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040134:nhr-49(RNAi)_regulated_protein
      WBPaper00041954:ethanol_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:endoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049979:R-astaxanthin_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_HighSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050887:Lactoferrin_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051388:Glucose-diet_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_upregulated
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061527:dhs-28_22199-acs-14
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065392:Lb.delbrueckii_upregulated
      WBPaper00065392:Lb.gasseri_upregulated
      WBPaper00065392:Lb.rhamnosus_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066005:RAGA-1_degradation_somatic_upregulated
      cgc4386_cluster_1_6
      cgc4489_group_5
      WBPaper00025032:cluster_16
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00028789:PA14_vs_gacA_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00031003:hlh_1_enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036286:Pattern_C
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040963:Q50_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041906:I-3690_vs_OP50_10d
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050538:Fasting_upregulated_cholesterol-dependent
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (27)
  Map_info: Map: V Position: 4.73474
    Positive: Positive_clone: F54F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038108
    WBPaper00038491
    WBPaper00042191
    WBPaper00053370
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene