cids-2 encodes a protein that contains a CTD (C-terminal domain of RNA Pol II)-interacting domain and that is paralogous to CIDS-1; cids-2 was identified genetically as a suppressor of the SynMuv phenotype produced by lin-15AB(n765), a mutation that results in transposition of the 3'-end cleavage and polyadenylation signal of another gene into the third exon of lin-15B; qRT-PCR assays suggest that CIDS-2 plays a role in 3'-end cleavage.
Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD2 (regulation of nuclear pre-mRNA domain containing 2).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.