WormBase Tree Display for Gene: WBGene00004497

WBGene00004497 SMap: S_parent: Sequence: Y41D4B
  Identity: Version: 1
    Name: CGC_name: rps-28
      Sequence_name: Y41D4B.5
      Molecular_name: Y41D4B.5
        Y41D4B.5.1
        CE21842
      Other_name: CELE_Y41D4B.5 Accession_evidence: NDB BX284604
      Public_name: rps-28
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rps
    Allele: WBVar01499166
      WBVar00184333
      WBVar00184334
      WBVar00184335
      WBVar01499633
      WBVar01450844
      WBVar01500231
      WBVar01481287
    Legacy_information: Orthologous to yeast (S.cerevisiae) ribosomal protein rps28 using blastP
    RNASeq_FPKM (74)
    GO_annotation (18)
    Contained_in_operon: CEOP4640
    Ortholog (21)
    Structured_description: Concise_description: rps-28 encodes a small ribosomal subunit S28 protein. Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; maturation of SSU-rRNA; and ribosomal small subunit assembly. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic small ribosomal subunit and polysomal ribosome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 15 with mandibulofacial dysostosis. Is an ortholog of human RPS28 (ribosomal protein S28). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111894 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10418)
  Molecular_info: Corresponding_CDS: Y41D4B.5
    Corresponding_transcript: Y41D4B.5.1
    Other_sequence (506)
    Associated_feature: WBsf645812
      WBsf981675
      WBsf995500
      WBsf995501
      WBsf995502
      WBsf995503
      WBsf1016769
      WBsf1016770
      WBsf227967
      WBsf227968
  Experimental_info: RNAi_result (22)
    Expr_pattern (5)
    Microarray_results (18)
    Expression_cluster: WBPaper00028451:Low_abundance_spermatogenesis_enriched
      WBPaper00032009:nhr-40(ok667)_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00036662:oxidative_modification
      WBPaper00037047:insoluble_protein
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038118:stress_downregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040446:insoluble_protein
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045521:Spermatogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046499:AMPK_regulated
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050234:lin-28(RNAi)_downregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00059194:KLF-1_interacting
      WBPaper00059254:CSR-1_interacting
      WBPaper00059254:PRG-1_interacting
      WBPaper00059254:WAGO-1_interacting
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060908:TEBP-1_interacting
      WBPaper00060908:TEBP-2_interacting
      WBPaper00061285:wounding_0h_downregulated
      WBPaper00061285:wounding_24h_downregulated
      WBPaper00061340:M_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:rps-14_21270-rps-11_20714
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:ADE_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:Excretory_gland_cell_enriched
      WBPaper00061651:Germline_enriched
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:M1_enriched
      WBPaper00061651:M2_enriched
      WBPaper00061651:MI_enriched
      WBPaper00061651:NSM_enriched
      WBPaper00061651:PDB_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_upregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:let-7_miRNA_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064257:UNG-1_interacting
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00024671:AFD_vs_AWB_upregulated
      WBPaper00025032:cluster_10
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00037147:heatshock_upregulated
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00042548:miRISC_enriched
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (169)
  Map_info: Map: IV Position: -16.2539 Error: 0.005704
    Positive: Positive_clone: Y41D4B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00035149
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00062388
    WBPaper00065026
  Remark: rps-28 is described as "Orthologous to yeast (S.cerevisiae) ribosomal protein rps28 using blastP". BlastP of C. elegans with sp|P02380|RS28_YEAST gives the hit Y41D4B.5 Person_evidence: WBPerson567
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene