WormBase Tree Display for Gene: WBGene00004465

WBGene00004465 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: T06D8
  Identity: Version: 1
    Name: CGC_name: rpn-9 Person_evidence: WBPerson1551
      Sequence_name: T06D8.8
      Molecular_name: T06D8.8
        T06D8.8.1
        CE02329
      Other_name: CELE_T06D8.8 Accession_evidence: NDB BX284602
      Public_name: rpn-9
    DB_info: Database: AceView gene 2L528
        WormQTL gene WBGene00004465
        WormFlux gene WBGene00004465
        NDB locus_tag CELE_T06D8.8
        Panther gene CAEEL|WormBase=WBGene00004465|UniProtKB=Q22253
          family PTHR10539
        NCBI gene 174715
        RefSeq protein NM_064004.8
        TREEFAM TREEFAM_ID TF105612
        TrEMBL UniProtAcc Q22253
        UniProt_GCRP UniProtAcc Q22253
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rpn
    Allele (16)
    Strain: WBStrain00036223
      WBStrain00054676
      WBStrain00054679
    Component_of_genotype: WBGenotype00000100
    RNASeq_FPKM (74)
    GO_annotation: 00074684
      00074685
      00074686
      00074687
      00074688
      00074689
      00074690
      00074691
      00074692
      00074693
    Contained_in_operon: CEOP2524
    Ortholog (35)
    Structured_description: Concise_description: rpn-9 is predicted to encode a non-ATPase subunit of the 19S regulatory complex of the proteasome that that affects body morphology, embryonic viability, locomotion, larval viability, fertility, and growth; interacts with RPN-11 in yeast two-hybrid assays. Paper_evidence: WBPaper00004888
            WBPaper00005599
            WBPaper00005654
            WBPaper00006395
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable structural molecule activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD13 (proteasome 26S subunit, non-ATPase 13). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Modifies_disease: DOID:332
    DOID:9255
  Modifies_disease_in_annotation: WBDOannot00001141
    WBDOannot00001142
  Molecular_info: Corresponding_CDS: T06D8.8
    Corresponding_transcript: T06D8.8.1
    Other_sequence (81)
    Associated_feature: WBsf650554
      WBsf650555
      WBsf650556
      WBsf981282
      WBsf223910
      WBsf223911
  Experimental_info: RNAi_result (26)
    Expr_pattern: Chronogram435
      Expr6621
      Expr1027703
      Expr1032268
      Expr1156253
      Expr2015497
      Expr2033732
    Drives_construct: WBCnstr00003961
      WBCnstr00035464
    Construct_product: WBCnstr00035464
    Microarray_results (22)
    Expression_cluster: WBPaper00027057:DCR-1_interacting_adult
      WBPaper00028451:Oogenic_protein
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044128:DietaryRestriction_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049177:rpn-10(ok1865)_upregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053615:SMO-1_target
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056997:NMAD-1_interacting
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061527:pbs-3_18439-rpn-5
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062123:GLH-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064201:SNA-3_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_4
      WBPaper00025032:cluster_4
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00032948:FedUp
      WBPaper00034739:N2moreDR1350
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(66_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_F
      [cgc6390]:oogenesis-enriched
    Interaction (193)
  Map_info (4)
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene