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WormBase Tree Display for Gene: WBGene00004193

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Name Class

WBGene00004193EvidencePaper_evidenceWBPaper00005877
SMapS_parentSequenceC15H9
IdentityVersion2
NameCGC_nameprx-3
Sequence_nameC15H9.8
Molecular_nameC15H9.8a
C15H9.8a.1
CE41868
C15H9.8b
CE06836
C15H9.8b.1
Other_nameCELE_C15H9.8Accession_evidenceNDBBX284606
Public_nameprx-3
DB_infoDatabase (10)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
230 Nov 2007 08:46:02WBPerson1867EventAcquires_mergeWBGene00015804
Acquires_mergeWBGene00015804
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classprx
Allele (32)
RNASeq_FPKM (74)
GO_annotation00059997
00059998
00059999
00060000
00112464
00112465
Ortholog (34)
Structured_descriptionConcise_descriptionprx-3 is orthologous to the human gene PEROXISOMAL BIOGENESIS FACTOR 3 (PEX3; OMIM:603164), which when mutated leads to Zellweger syndrome of complementation group G.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein-macromolecule adaptor activity. Predicted to be involved in protein import into peroxisome membrane. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 10A. Is an ortholog of human PEX3 (peroxisomal biogenesis factor 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080484Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8858)
DOID:0080377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8858)
Molecular_infoCorresponding_CDSC15H9.8a
C15H9.8b
Corresponding_CDS_historyC15H9.8:wp185
Corresponding_transcriptC15H9.8a.1
C15H9.8b.1
Other_sequenceCJC03027_1
CRC00430_1
CR08385
Tcir_isotig25493
CBC11882_1
Associated_featureWBsf654045
WBsf237441
WBsf237442
Experimental_infoRNAi_result (11)
Expr_patternExpr1017263
Expr1032053
Expr1144693
Expr2015126
Expr2033364
Construct_productWBCnstr00022628
Microarray_results (37)
Expression_clusterWBPaper00037086:biotin_regulated
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_CoreEnriched
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_embryo_SelectivelyEnriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:intestine_larva_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00040134:nhr-49(RNAi)_regulated_protein
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044030:nhr-8(hd117)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00046121:endoderm_unique
WBPaper00046509:lin-35(n745)_downregulated
WBPaper00048690:gonad-male-biased
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050080:rbr-2(tm3141)_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051245:cytoplasm_specific
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051558:aging_regulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
WBPaper00055137:S.maltophilia_downregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056284:ints-9(RNAi)_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:set-2(bn129)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059839:S.maltophilia_regulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060661:sensory-neuron_enriched
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061007:X.citri_upregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ALM_BDU
WBPaper00061340:hyp4_hyp5_hyp6
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:P_cell
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:dhs-28_22199-acs-14
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062554:MAGU-2_interacting
WBPaper00064071:NHR-49_interacting
WBPaper00064130:Beta-Amyloid_upregulated_protein
WBPaper00064716:paraquat_downregulated
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065841:49_0
WBPaper00065841:62_0
WBPaper00065841:102_0
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065984:pals-17(syb3980)_downregulated
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00024671:AFD_vs_AWB_upregulated
WBPaper00025032:cluster_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00028474:dys-1_upregulated
WBPaper00032062:age_regulated_genes
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036286:Pattern_C
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00040210:Diazinon_24C_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_developing
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00040876:mir-35_upregulated
WBPaper00040963:Q100_down
WBPaper00041002:HF_3d_0.2mM_Up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00055899:nitroguanidine_regulated
[cgc5767]:cluster_2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(83_min)
[cgc5767]:expression_class_E_pi(101_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(83_min)
[cgc5767]:expression_class_SE_pi(101_min)
[cgc6390]:Cluster_B
InteractionWBInteraction000036526
WBInteraction000181958
WBInteraction000280074
WBInteraction000325933
WBInteraction000346563
WBInteraction000383669
WBInteraction000575899
WBInteraction000585711
WBInteraction000586669
Map_infoMapXPosition-3.70322
PositivePositive_cloneC15H9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005877
WBPaper00006517
WBPaper00038491
WBPaper00055090
WBPaper00056693
WBPaper00059323
WBPaper00064552
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene