WormBase Tree Display for Gene: WBGene00003990

WBGene00003990 Evidence: Person_evidence: WBPerson463
  SMap: S_parent: Sequence: F35C8
  Identity: Version: 1
    Name: CGC_name: pfn-2 Person_evidence: WBPerson75
      Sequence_name: F35C8.6
      Molecular_name: F35C8.6
        F35C8.6.1
        CE39098
      Other_name: CELE_F35C8.6 Accession_evidence: NDB BX284606
      Public_name: pfn-2
    DB_info: Database: AceView gene XF972
        WormQTL gene WBGene00003990
        WormFlux gene WBGene00003990
        NDB locus_tag CELE_F35C8.6
        Panther gene CAEEL|WormBase=WBGene00003990|UniProtKB=Q20025
          family PTHR11604
        NCBI gene 180808
        RefSeq protein NM_076509.7
        SwissProt UniProtAcc Q20025
        TREEFAM TREEFAM_ID TF300134
        UniProt_GCRP UniProtAcc Q20025
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pfn
    Allele (34)
    Strain: WBStrain00001781
      WBStrain00031432
      WBStrain00034783
    RNASeq_FPKM (74)
    GO_annotation (9)
    Ortholog (29)
    Paralog: WBGene00003989 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00003991 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable actin monomer binding activity. Involved in muscle thin filament assembly. Predicted to be located in cell cortex. Expressed in pharynx and spermatheca. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F35C8.6
    Corresponding_CDS_history: F35C8.6:wp148
    Corresponding_transcript: F35C8.6.1
    Other_sequence (35)
    Associated_feature: WBsf653973
      WBsf655660
      WBsf982169
      WBsf1005243
      WBsf1005244
      WBsf1022939
  Experimental_info: RNAi_result: WBRNAi00014311 Inferred_automatically: RNAi_primary
      WBRNAi00022830 Inferred_automatically: RNAi_primary
      WBRNAi00098006 Inferred_automatically: RNAi_primary
      WBRNAi00098007 Inferred_automatically: RNAi_primary
      WBRNAi00046313 Inferred_automatically: RNAi_primary
      WBRNAi00065249 Inferred_automatically: RNAi_primary
      WBRNAi00080815 Inferred_automatically: RNAi_primary
      WBRNAi00098008 Inferred_automatically: RNAi_primary
      WBRNAi00031766 Inferred_automatically: RNAi_primary
      WBRNAi00090684 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3808
      Expr3810
      Expr5951
      Expr1017939
      Expr1031906
      Expr1150201
      Expr1200230
      Expr2014852
      Expr2033087
    Drives_construct: WBCnstr00002594
      WBCnstr00011670
      WBCnstr00035760
    Construct_product: WBCnstr00035760
    Antibody: WBAntibody00001033
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00032976:non_compensated_genes
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_tiling
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:CAN
      WBPaper00061340:Excretory_gland
      WBPaper00061340:Posterior_arcade_cell
      WBPaper00061340:RMED
      WBPaper00061340:Tail_hypodermis
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:tars-1-AFFX-r2-3026-5_at
      WBPaper00061651:Spermatheca_enriched
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065841:11_2
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_2_3
      cgc4489_group_3
      WBPaper00025099:MA_specific
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026980:intestine_enriched
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_I
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_C
    Interaction: WBInteraction000292439
      WBInteraction000413841
      WBInteraction000521744
      WBInteraction000551423
      WBInteraction000565977
      WBInteraction000576035
      WBInteraction000577677
      WBInteraction000580238
  Map_info: Map: X Position: -5.55565 Error: 0.033757
    Positive: Positive_clone: F35C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4780
        4449
    Pseudo_map_position
  Reference: WBPaper00024757
    WBPaper00026958
    WBPaper00032338
    WBPaper00033162
    WBPaper00049828
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene