WormBase Tree Display for Gene: WBGene00003544

WBGene00003544 Evidence: Author_evidence: Moehrlen F
  SMap: S_parent: Sequence: F46C5
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: nas
    Allele (37)
    Strain: WBStrain00002601
      WBStrain00037798
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (33)
    Paralog (48)
    Structured_description: Concise_description: nas-25 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-25::GFP promoter fusion is expressed in the pharynx and pharyngeal-intestinal valve. Paper_evidence: WBPaper00006254
            WBPaper00006525
            WBPaper00031006
          Curator_confirmed: WBPerson1843
          Date_last_updated: 15 Feb 2008 00:00:00
      Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in arcade cell; marginal cell; and rectal gland cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46C5.3
    Corresponding_CDS_history: F46C5.3:wp61
    Corresponding_transcript: F46C5.3.1
    Other_sequence: SRC00539_1
      SSC00042_1
      SS01464
      Hbac_isotig02723
      FC815339.1
      SS00066
      FC809974.1
    Associated_feature: WBsf988831
      WBsf1012752
      WBsf221821
  Experimental_info: RNAi_result: WBRNAi00089083 Inferred_automatically: RNAi_primary
      WBRNAi00047507 Inferred_automatically: RNAi_primary
      WBRNAi00032355 Inferred_automatically: RNAi_primary
      WBRNAi00015076 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1247
      Expr6086
      Expr8922
      Expr1013949
      Expr1151347
      Expr2013874
      Expr2032114
    Drives_construct: WBCnstr00003159
      WBCnstr00013617
      WBCnstr00036055
    Construct_product: WBCnstr00013617
      WBCnstr00036055
    Microarray_results (24)
    Expression_cluster: WBPaper00029359_1166
      WBPaper00029359_1197
      WBPaper00029359_1291
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045774:clk-1_upregulated
      WBPaper00046024:sleep_upregulated_oscillating
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055226:adr-1(tm668)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
      WBPaper00058678:DAF-12_upregulated_PVD
      WBPaper00058969:RIS_depleted
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:hypoxia_downregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00061340:Arcade_cell_anterior_and_posterior
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061527:T16H12.9-kin-9_20752
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065841:15_0
      WBPaper00065841:24_1
      WBPaper00065841:30_4
      WBPaper00065841:41_0
      WBPaper00065841:41_1
      WBPaper00065841:41_2
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_14
      WBPaper00025032:cluster_181
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032948:FedUp
      WBPaper00036123:Atrazine_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045015:acs-3(ft5)_upregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
    Interaction (3)
  Map_info: Map: II Position: 0.903735 Error: 0.000817
    Positive: Positive_clone: F46C5 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006254
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene