WormBase Tree Display for Gene: WBGene00002002

WBGene00002002 SMap: S_parent: Sequence: K08E7
  Identity: Version: 1
    Name: CGC_name: hsb-1 Person_evidence: WBPerson345
      Sequence_name: K08E7.2
      Molecular_name: K08E7.2
        K08E7.2.1
        CE23864
        K08E7.2.2
        K08E7.2.3
      Other_name: CELE_K08E7.2 Accession_evidence: NDB BX284604
      Public_name: hsb-1
    DB_info: Database: AceView gene 4N330
        WormQTL gene WBGene00002002
        WormFlux gene WBGene00002002
        NDB locus_tag CELE_K08E7.2
        Panther gene CAEEL|WormBase=WBGene00002002|UniProtKB=Q9U3B7
          family PTHR19424
        NCBI gene 178208
        RefSeq protein NM_001392417.1
        TREEFAM TREEFAM_ID TF314005
        TrEMBL UniProtAcc Q9U3B7
        UniProt_GCRP UniProtAcc Q9U3B7
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hsb
    Allele (25)
    Legacy_information: [Kramer JM] hsb for Heat Shock factor Binding protein. Deletion is viable, abnormal, possibly cold-sensitive. Overexpression leads to heat-sensitiviy. Predicted gene K08E7.2
    Strain: WBStrain00001943
      WBStrain00005028
    RNASeq_FPKM (74)
    GO_annotation: 00100081
      00100082
      00100083
      00100084
      00100085
      00100086
      00100087
      00100088
      00109863
    Contained_in_operon: CEOP4520
    Ortholog (27)
    Structured_description: Automated_description: Predicted to enable transcription corepressor activity. Predicted to be involved in cellular heat acclimation. Predicted to be located in cytosol and nucleus. Is an ortholog of human HSBP1 (heat shock factor binding protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K08E7.2
    Corresponding_transcript: K08E7.2.1
      K08E7.2.2
      K08E7.2.3
    Other_sequence (37)
    Associated_feature: WBsf652303
      WBsf668436
      WBsf998161
      WBsf1018392
  Experimental_info: RNAi_result: WBRNAi00016815 Inferred_automatically: RNAi_primary
      WBRNAi00050303 Inferred_automatically: RNAi_primary
      WBRNAi00034143 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6366
      Expr1024759
      Expr1031167
      Expr1154005
      Expr2012605
      Expr2030841
    Drives_construct (7)
    Construct_product: WBCnstr00000357
      WBCnstr00007147
      WBCnstr00036529
    Regulate_expr_cluster: WBPaper00056446:hsb-1(cg116)_downregulated
      WBPaper00056446:hsb-1(cg116)_upregulated
    Microarray_results (22)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00038061:aldicarb_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054626:NO_upregulated
      WBPaper00056446:hsb-1(cg116)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00059471:EGL-43_interacting
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061527:F43G9.13-F33D11.12
      WBPaper00061527:snr-3-rbx-1
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_downregulated_N2_protein
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      cgc4489_group_5
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00034739:N2lessDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038427:lin-54_germline_changed
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (77)
    WBProcess: WBbiopr:00000001
  Map_info: Map: IV Position: 6.02389
    Positive: Positive_clone: K08E7 Person_evidence: WBPerson345
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4415
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene