WormBase Tree Display for Gene: WBGene00001331

WBGene00001331 SMap: S_parent: Sequence: F09B9
  Identity: Version: 2
    Name: CGC_name: erd-2.1 Person_evidence: WBPerson261
      Sequence_name: F09B9.3
      Molecular_name: F09B9.3
        F09B9.3.1
        CE23635
      Other_name: ERD2 Accession_evidence: EMBL AF081125
        erd-2 Person_evidence: WBPerson261
        sup-2 Person_evidence: WBPerson261
        CELE_F09B9.3 Accession_evidence: NDB BX284606
      Public_name: erd-2.1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 08 Nov 2018 16:58:35 WBPerson1983 Name_change: CGC_name: erd-2.1
                Other_name: erd-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: erd
    Allele (26)
    Strain (2)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (43)
    Paralog: WBGene00016195 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: erd-2 encodes a protein with homology to human ER lumen protein retaining receptor 1. Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable ER retention sequence binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cis-Golgi network and endoplasmic reticulum. Expressed in head and tail. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Is an ortholog of human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112201 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6305)
  Molecular_info: Corresponding_CDS: F09B9.3
    Corresponding_transcript: F09B9.3.1
    Other_sequence (49)
    Associated_feature: WBsf654307
      WBsf670925
      WBsf670926
      WBsf670927
      WBsf670928
      WBsf237837
  Experimental_info: RNAi_result: WBRNAi00044081 Inferred_automatically: RNAi_primary
      WBRNAi00076282 Inferred_automatically: RNAi_primary
      WBRNAi00012951 Inferred_automatically: RNAi_primary
      WBRNAi00086443 Inferred_automatically: RNAi_primary
      WBRNAi00086442 Inferred_automatically: RNAi_primary
      WBRNAi00027781 Inferred_automatically: RNAi_primary
      WBRNAi00086441 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1258
      Expr5691
      Expr1024480
      Expr1030811
      Expr1148047
      Expr2011355
      Expr2029591
    Drives_construct: WBCnstr00003490
      WBCnstr00036994
    Construct_product: WBCnstr00036994
    Microarray_results (19)
    Expression_cluster: WBPaper00027022:tax-6(jh107)_downregulated
      WBPaper00029359_1291
      WBPaper00032425:up_in_alg-1
      WBPaper00032425:up_in_rde-4
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00032976:dosage_compensated_genes
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037946:EGL-5_interacting
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00051558:aging_regulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061340:G2_and_W_blasts
      WBPaper00061340:hmc_and_homolog
      WBPaper00061340:Parents_of_PHsh_hyp8_hyp9
      WBPaper00061340:Parent_of_tail_spike_and_hyp10
      WBPaper00061340:T
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:K10C9.3_8160-Y39G8B.1_58
      WBPaper00061527:uggt-1_21889-tag-320_20312
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:SIA_enriched
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065158:AFD_depleted
      cgc4386_cluster_4_6
      cgc4489_group_7
      WBPaper00025032:cluster_10
      WBPaper00025032:cluster_138
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:FedUp
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_B
    Interaction (65)
  Map_info: Map: X Position: 1.86492
    Positive: Positive_clone: F09B9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028381
    WBPaper00038491
    WBPaper00055090
    WBPaper00058518
    WBPaper00061353
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene