WormBase Tree Display for Gene: WBGene00000010

WBGene00000010 Evidence: Author_evidence: Veljkovic E
      Verrey F
  SMap: S_parent: Sequence: Y53H1C
  Identity: Version: 1
    Name: CGC_name: aat-9
      Sequence_name: Y53H1C.1
      Molecular_name: Y53H1C.1a
        Y53H1C.1a.1
        CE22438
        Y53H1C.1b
        CE38453
        Y53H1C.1b.1
      Other_name: CELE_Y53H1C.1 Accession_evidence: NDB BX284601
      Public_name: aat-9
    DB_info: Database: WormQTL gene WBGene00000010
        WormFlux gene WBGene00000010
        NDB locus_tag CELE_Y53H1C.1
        Panther gene CAEEL|WormBase=WBGene00000010|UniProtKB=Q9NA91
          family PTHR11785
        NCBI gene 190250
        RefSeq protein NM_001026617.5
            NM_001026618.5
        TrEMBL UniProtAcc Q56VY0
            Q9NA91
        UniProt_GCRP UniProtAcc Q9NA91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:19 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aat
    Allele (151)
    RNASeq_FPKM (74)
    GO_annotation: 00081168
      00081169
      00081170
      00081171
      00081172
      00081173
      00106538
      00106539
      00106540
    Contained_in_operon: CEOP1950
    Ortholog (32)
    Paralog (12)
    Structured_description: Concise_description: aat-9 encodes an amino acid transporter catalytic subunit; AAT-9 lacks the conserved cysteine residue proposed to be essential for association with a glycoprotein subunit, and when expressed alone in Xenopus ooctyes, AAT-9 can localize to the cell surface and function as an aromatic amino acid exchanger that displays substrate-activated anion conductance; nevertheless, AAT-9 activity is enhanced by co-expression with the ATG-1 and ATG-2 glycoprotein subunits; an aat-9::gfp promoter fusion directs expression in anterior neurons, including some chemosensory neurons, as well as in some anterior body wall muscles. Paper_evidence: WBPaper00006408
            WBPaper00024381
          Curator_confirmed: WBPerson1843
          Date_last_updated: 03 Mar 2006 00:00:00
      Automated_description: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Located in cell surface. Expressed in body wall musculature and neurons. Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y53H1C.1a
      Y53H1C.1b
    Corresponding_transcript: Y53H1C.1a.1
      Y53H1C.1b.1
    Associated_feature: WBsf976578
      WBsf976579
      WBsf220332
      WBsf220333
  Experimental_info: RNAi_result: WBRNAi00116961 Inferred_automatically: RNAi_primary
      WBRNAi00004721 Inferred_automatically: RNAi_primary
      WBRNAi00037450 Inferred_automatically: RNAi_primary
      WBRNAi00004720 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3122
      Expr1016320
      Expr1030005
      Expr1160770
      Expr2009072
      Expr2027308
    Drives_construct: WBCnstr00011152
    Antibody: WBAntibody00000794
    Microarray_results (26)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033070:Elbe_upregulated
      WBPaper00033070:Rhine_upregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061527:rsp-4_18519-htz-1_18194
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_11
      cgc4489_group_12
      WBPaper00025032:cluster_32
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045673:colistin_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050538:Fasting_upregulated
      [cgc5767]:cluster_48
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(101_min)
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
    Interaction: WBInteraction000140033
      WBInteraction000279960
      WBInteraction000322665
      WBInteraction000463823
      WBInteraction000579834
  Map_info: Map: I Position: 7.96457 Error: 0.003257
    Positive: Positive_clone: Y53H1C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006408
    WBPaper00024381
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene