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WormBase Tree Display for Gene: WBGene00003864

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Name Class

WBGene00003864SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion1
NameCGC_nameoma-1Person_evidenceWBPerson374
Sequence_nameC09G9.6
Molecular_nameC09G9.6
C09G9.6.1
CE03005
Other_namemoe-1
CELE_C09G9.6Accession_evidenceNDBBX284604
Public_nameoma-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classoma
Allele (56)
StrainWBStrain00035069
WBStrain00035066
WBStrain00035067
WBStrain00035068
WBStrain00040433
WBStrain00040434
WBStrain00048324
WBStrain00052677
RNASeq_FPKM (74)
GO_annotation (55)
Contained_in_operonCEOP4312
Ortholog (51)
Paralog (20)
Structured_descriptionConcise_descriptionoma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization.Paper_evidenceWBPaper00005198
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated19 Mar 2012 00:00:00
Automated_descriptionEnables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0014769Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1108)
Molecular_infoCorresponding_CDSC09G9.6
Corresponding_transcriptC09G9.6.1
Other_sequenceXIC01512_1
HG11531
XI03775
SRC08713_1
FC813056.1
Associated_feature (15)
Gene_product_bindsWBsf034245
Transcription_factorWBTranscriptionFactor000116
Experimental_infoRNAi_result (29)
Expr_pattern (16)
Drives_construct (13)
Construct_product (14)
AntibodyWBAntibody00000486
WBAntibody00000547
WBAntibody00001073
WBAntibody00001074
WBAntibody00001087
WBAntibody00001664
WBAntibody00002447
Microarray_results (20)
Expression_clusterWBPaper00028451:Oogenic_protein
WBPaper00028867:HLH-1_induced_TF
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032097:CGH-1-associated-mRNA
WBPaper00035269:cde-1_regulated
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00041222:unc-120(st364)_downregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:rising_dev_expression
WBPaper00044760:germline_specific
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
WBPaper00045050:drh-3 (ne4253)_downregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Oogenic
WBPaper00045618:puf-8_downregulated
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046012:tdp-1(ok803)_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048611:MnCl2_downregulated
WBPaper00048762:FOG-3_associated
WBPaper00048988:neuron_expressed
WBPaper00049159:Microwave_upregulated_L4
WBPaper00049498:npr-1(ur89)_regulated_6
WBPaper00049920:Glucose-Diet_downregulated_N2
WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050522:mafr-1(tm6082)_downregulated
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051039:germline_enriched
WBPaper00051265:F1_morc-1(tm6048)_downregulated
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051310:LIN-41_interacting
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053154:human-amyloid-beta_tau_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(icb38)_downregulated
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_embryo_SMARTseq
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
WBPaper00054191:H3.3(null)_L1_upregulated
WBPaper00054792:FOG-3_interacting
WBPaper00055049:S.gordonii_downregulated
WBPaper00055103:thoc-5(wy822)_downregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Metformin_downregulated
WBPaper00055354:Rapamycin-Allantoin_upregulated
WBPaper00055354:Rapamycin_upregulated
WBPaper00055648:germline_expressed
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055941:atfs-1(et15)_downregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056290:hsp-6(mg585)_downregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056826:hmc_biased
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057154:HeatShock_downregulated_mRNA
WBPaper00057154:HeatShock_upregulated_miRNA-target
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:mex-1(or286)_downregulated
WBPaper00058598:mex-3(eu149)_downregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:sin-3(tm1276)_upregulated
WBPaper00059027:neuron-synapses_enriched
WBPaper00059174:MEG-3_interacting
WBPaper00059254:CSR-1_interacting
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00059728:5ug_cholesterol_downregulated
WBPaper00059739:hira-1(gk835598)_upregulated_L4
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_upregulated_L4
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061045:Y56A3A.22(cck200)_downregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061203:spr-1(ok2144)_downregulated
WBPaper00061274:hypergravity_15xg_upregulated
WBPaper00061340:ALM_BDU
WBPaper00061340:ASG_AWA
WBPaper00061340:ASI_parent
WBPaper00061340:Neuroblast_ASG_AWA
WBPaper00061340:OLL_parent
WBPaper00061340:OLQ_parent
WBPaper00061527:puf-3-oma-2_18268
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061818:ELKS-1_interacting
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062118:neural-HSF-1_upregulated
WBPaper00062123:GLH-1_interacting
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062440:crh-1(n3315)_upregulated
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00062587:lsl-1(ljm1)_downregulated
WBPaper00062587:lsl-1(tm4769)_downregulated
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064502:spe-44(fx110)_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00064871:hypoxia_upregulated_F1
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065158:25C_vs_15C_upregulated_AFD
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00065984:pals-17(syb3980)_upregulated
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4489_group_9
WBPaper00005124:cholesterol_10-9M_regulated
WBPaper00025032:cluster_56
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00032165:differentially_expressed_with_age_medoid_3
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036130:mir-243_down_regulated
WBPaper00036286:Pattern_F
WBPaper00037147:heatshock_upregulated
WBPaper00037611:RNP-8-associated
WBPaper00037901:GLD-1_mRNA_targets
WBPaper00040426:CYD-1_CDK-4_upregulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_developing
WBPaper00041002:HF_11d_2.0mM_Up
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00048624:hlh-25(ok1710)_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00051387:Triclosan_downregulated
WBPaper00056330:mrps-5(RNAi)_downregulated
[cgc5767]:cluster_3
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(41_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
[cgc6390]:Cluster_E
[cgc6390]:oogenesis-enriched
Interaction (354)
WBProcessWBbiopr:00000068
WBbiopr:00000073
Map_infoMapIVPosition3.99916Error0.001096
PositivePositive_cloneC09G9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point7138
Multi_point4054
4056
4064
4065
ReferenceWBPaper00005198
WBPaper00005454
WBPaper00005930
WBPaper00006085
WBPaper00010630
WBPaper00010668
WBPaper00010802
WBPaper00012537
WBPaper00017837
WBPaper00017838
WBPaper00018617
WBPaper00018755
WBPaper00018768
WBPaper00018887
WBPaper00019036
WBPaper00023917
WBPaper00024312
WBPaper00024507
WBPaper00025650
WBPaper00025747
WBPaper00026080
WBPaper00026378
WBPaper00026516
WBPaper00026970
WBPaper00026975
WBPaper00027080
WBPaper00027224
WBPaper00027238
WBPaper00027298
WBPaper00027309
WBPaper00027310
WBPaper00027320
WBPaper00027607
WBPaper00027739
WBPaper00028423
WBPaper00028730
WBPaper00031129
WBPaper00031702
WBPaper00031842
WBPaper00031867
WBPaper00032146
WBPaper00032265
WBPaper00032287
WBPaper00033085
WBPaper00033447
WBPaper00034932
WBPaper00035436
WBPaper00036019
WBPaper00036909
WBPaper00037129
WBPaper00037685
WBPaper00038491
WBPaper00038621
WBPaper00038735
WBPaper00038743
WBPaper00039209
WBPaper00039584
WBPaper00039588
WBPaper00039589
WBPaper00041400
WBPaper00042062
WBPaper00042959
WBPaper00043308
WBPaper00043745
WBPaper00043747
WBPaper00044147
WBPaper00044760
WBPaper00045802
WBPaper00045803
WBPaper00046178
WBPaper00048493
WBPaper00048539
WBPaper00048543
WBPaper00050819
WBPaper00051310
WBPaper00052021
WBPaper00052136
WBPaper00055090
WBPaper00056632
WBPaper00057125
WBPaper00057140
WBPaper00057808
WBPaper00057881
WBPaper00058597
WBPaper00059332
WBPaper00061125
WBPaper00061137
WBPaper00062120
WBPaper00062457
WBPaper00063103
WBPaper00063533
WBPaper00063960
WBPaper00064664
WBPaper00066192
PictureWBPicture0000013094
RemarkWeak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1]
Sequence connection based on Lin, R [021017 ck1]
Sequence connection from [Shimada M], [krb 020711]
Postitive method is weak rescue of the zu405 embryonic lethality
MethodGene