rpa-2 encodes the C. elegans homolog of the medium subunit of replication protein A (RPA); by homology RPA-2 is predicted to function in several DNA metabolic processes, including recombination, repair, and replication, as well as cell cycle and DNA damage checkpoints; RPA-2 physically interacts with RPA-1, the RPA large subunit, in vivo.
Enables enzyme binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. Expressed in pharyngeal neurons and seam cell. Is an ortholog of human RPA2 (replication protein A2).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.