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WormBase Tree Display for Gene: WBGene00010780

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Name Class

WBGene00010780SMapS_parentSequenceK11H3
IdentityVersion1
NameSequence_nameK11H3.3
Molecular_nameK11H3.3
K11H3.3.1
CE00474
Other_nameCELE_K11H3.3Accession_evidenceNDBBX284603
Public_nameK11H3.3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (27)
RNASeq_FPKM (74)
GO_annotation00042763
00042764
00042765
00042766
00042767
00042768
00042769
Ortholog (42)
Paralog (35)
Structured_descriptionAutomated_descriptionPredicted to enable citrate secondary active transmembrane transporter activity. Predicted to be involved in mitochondrial citrate transmembrane transport. Predicted to be located in mitochondrion. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in combined D-2- and L-2-hydroxyglutaric aciduria and congenital myasthenic syndrome. Is an ortholog of human SLC25A1 (solute carrier family 25 member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0060413Homo sapiensPaper_evidenceWBPaper00047004
Curator_confirmedWBPerson324
Date_last_updated20 Sep 2018 00:00:00
Potential_modelDOID:0111619Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10979)
DOID:3635Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10979)
DOID:0050573Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10979)
Disease_relevance22q11.2 deletion syndrome (22q11.2DS) is the most common human deletion syndrome caused by deletion of a small piece of chromosome 22, characterized by neurodevelopmental defects, schizophrenia, congenital cardiac and craniofacial abnormalites (includes DiGeorge Syndrome and velocardiofacial syndrome); the 22q11.2 deletion overlaps several protein-coding genes including SLC25A1 (solute carrier family 25, mitochondrial carrier, citrate transporter); C. elegans K11H3.3 encodes a putative ortholog of human SLC25A1, providing a potential model system to study 22q11.2DS.Homo sapiensPaper_evidenceWBPaper00047004
Accession_evidenceOMIM615182
611867
190315
Curator_confirmedWBPerson324
Date_last_updated15 Sep 2015 00:00:00
Models_disease_in_annotationWBDOannot00000364
Molecular_infoCorresponding_CDSK11H3.3
Corresponding_transcriptK11H3.3.1
Other_sequence (94)
Associated_featureWBsf659457
WBsf717098
WBsf993821
WBsf993822
WBsf1015679
WBsf225642
Experimental_infoRNAi_resultWBRNAi00034304Inferred_automaticallyRNAi_primary
WBRNAi00050636Inferred_automaticallyRNAi_primary
WBRNAi00007012Inferred_automaticallyRNAi_primary
WBRNAi00017040Inferred_automaticallyRNAi_primary
WBRNAi00050635Inferred_automaticallyRNAi_primary
Expr_patternExpr1024174
Expr1034719
Expr1154343
Expr2005083
Expr2023303
Drives_constructWBCnstr00031152
Construct_productWBCnstr00031152
Microarray_resultsSMD_K11H3.3
192057_at
A_12_P110926
Aff_K11H3.3
GPL13394_WBGene00010780
GPL13914_K11H3.3
GPL14144_K11H3.3_594-653_0.948_4_B
GPL14144_K11H3.3_699-758_0.954_1_A
GPL14144_K11H3.3_878-937_0.920_7_C
GPL19516_CGZ0029323
GPL21109_K11H3.3
GPL3518_CE00474
GPL8304_CE_WBGene00010780_A
GPL8304_CE_WBGene00010780_B
GPL8673_K11H3_3P00001
GPL8673_K11H3_3P00379
GPL8673_K11H3_3P00831
GPL9450_K11H3.3
cea2.c.21784
Expression_clusterWBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00035073:mitochondria_protein
WBPaper00037055:DAF-16_binding_DNA
WBPaper00037086:biotin_regulated
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_adult_enriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_embryo_enriched
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_CoreEnriched
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00041506:P3_enriched
WBPaper00044128:daf-2(e1370)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Oogenic
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00048910:mRNA-interacting_protein
WBPaper00048988:neuron_expressed
WBPaper00049495:starvation-refeeding_regulated
WBPaper00049498:npr-1(ur89)_regulated_6
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_nucleus_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00052987:UV_downregulated_xpc-1;csb-1
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00054192:cold-shock_downregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056165:MINA-1_interacting_mRNA
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056501:P.aeruginosa_upregulated_mitochondria-protein
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059471:EGL-43_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00059895:wounding_downregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:trcs-2_5724-R11A8.7_17645
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061653:alh-4(hj221)_upregulated
WBPaper00062293:isp-1(qm150)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062590:Aging_downregulated_hypodermis
WBPaper00063930:BRD-1_interacting
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064122:vulva_transcriptome
WBPaper00064624:iHg-induced_aggregome
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065158:AFD_enriched
WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027111:eri-1(mg366)_upregulated
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031832:slr-2_regulated
WBPaper00032165:differentially_expressed_with_age_medoid_6
WBPaper00035560:ahr-1_downregulated
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_G
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00045263:nuo-6(qm200)_upregulated
[cgc6390]:mixed_oogenesis-somatic
Interaction (36)
Map_infoPositivePositive_cloneK11H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIII1.12627
ReferenceWBPaper00038491
WBPaper00041771
WBPaper00049828
WBPaper00055090
WBPaper00064071
MethodGene