| WBGene00007443 | SMap | S_parent | Sequence | C08F8 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | pfd-1 | Person_evidence | WBPerson2136 |
| | | | | | WBPerson3663 |
| | | Sequence_name | C08F8.1 |
| | | Molecular_name | C08F8.1a |
| | | | C08F8.1a.1 |
| | | | CE05248 |
| | | | C08F8.1b |
| | | | CE45776 |
| | | | C08F8.1b.1 |
| | | Other_name | CELE_C08F8.1 | Accession_evidence | NDB | BX284604 |
| | | Public_name | pfd-1 |
| | DB_info | Database | AceView | gene | 4L915 |
| | | | WormQTL | gene | WBGene00007443 |
| | | | WormFlux | gene | WBGene00007443 |
| | | | NDB | locus_tag | CELE_C08F8.1 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00007443|UniProtKB=Q17827 |
| | | | | family | PTHR20903 |
| | | | NCBI | gene | 178021 |
| | | | RefSeq | protein | NM_001268612.4 |
| | | | | | NM_001268611.4 |
| | | | SwissProt | UniProtAcc | Q17827 |
| | | | TREEFAM | TREEFAM_ID | TF106490 |
| | | | UniProt_GCRP | UniProtAcc | Q17827 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 |
| | | | 2 | 02 Aug 2006 11:39:27 | WBPerson2970 | Name_change | CGC_name | pfd-1 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | pfd |
| | Allele (15) |
| | Strain | WBStrain00027643 |
| | | WBStrain00027644 |
| | | WBStrain00002703 |
| | | WBStrain00036248 |
| | RNASeq_FPKM (74) |
| | GO_annotation (13) |
| | Contained_in_operon | CEOP4420 |
| | Ortholog (29) |
| | Structured_description | Concise_description | pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration. | Paper_evidence | WBPaper00004651 |
| | | | | | WBPaper00005654 |
| | | | | | WBPaper00006395 |
| | | | | | WBPaper00024497 |
| | | | | | WBPaper00026660 |
| | | | | | WBPaper00031309 |
| | | | | | WBPaper00031362 |
| | | | | | WBPaper00031363 |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | Date_last_updated | 14 Jan 2008 00:00:00 |
| | | Automated_description | Predicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Expressed in head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN1 (prefoldin subunit 1). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C08F8.1a |
| | | C08F8.1b |
| | Corresponding_transcript | C08F8.1a.1 |
| | | C08F8.1b.1 |
| | Other_sequence (24) |
| | Associated_feature | WBsf646357 |
| | | WBsf229107 |
| Experimental_info | RNAi_result (34) |
| | Expr_pattern | Expr5210 |
| | | Expr7839 |
| | | Expr7844 |
| | | Expr9564 |
| | | Expr1028881 |
| | | Expr1033205 |
| | | Expr1144198 |
| | | Expr2014841 |
| | | Expr2033076 |
| | Drives_construct | WBCnstr00001362 |
| | | WBCnstr00001364 |
| | | WBCnstr00003245 |
| | | WBCnstr00033735 |
| | Construct_product | WBCnstr00033735 |
| | Microarray_results | SMD_C08F8.1 |
| | | 186761_at |
| | | A_12_P119103 |
| | | Aff_C08F8.1 |
| | | GPL13394_WBGene00007443 |
| | | GPL13914_C08F8.1 |
| | | GPL14144_C08F8.1_138-197_0.924_9_C |
| | | GPL14144_C08F8.1_189-248_0.928_7_B |
| | | GPL14144_C08F8.1_3-62_0.833_15_A |
| | | GPL19516_CGZ0003542 |
| | | GPL19516_CGZ0003543 |
| | | GPL21109_C08F8.1a |
| | | GPL21109_C08F8.1b |
| | | GPL3518_CE05248 |
| | | GPL8304_CE_WBGene00007443_A |
| | | GPL8304_CE_WBGene00007443_B |
| | | GPL8304_CE_WBGene00007443_C |
| | | GPL8673_C08F8_1P00150 |
| | | GPL8673_C08F8_1P00154 |
| | | GPL8673_C08F8_1P00295 |
| | | GPL9450_C08F8.1 |
| | | cea2.c.26258 |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00044426:rotenone_24h_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046303:P.aeruginosa_downregulated_protein |
| | | WBPaper00048926:miaserin_upregulated_adult-day5 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053388:dauer_regulated_Cluster1 |
| | | WBPaper00053599:oocyte_vs_mitosis_upregulated |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00055049:S.gordonii_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00056034:pals-25(jy9)_downregulated |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056284:ints-5(RNAi)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00058691:sin-3(tm1276)_downregulated |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00060014:set-2(zr2012)_upregulated |
| | | WBPaper00060459:bcat-1(RNAi)_downregulated |
| | | WBPaper00061341:28C_48h_downregulated |
| | | WBPaper00061527:lsm-4-F49C12.11_819 |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064122:vulva_transcriptome |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | cgc4489_group_4 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:Resveratrol_regulated_daf-16 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031252:AIN-2_IP_enriched |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_7 |
| | | WBPaper00032948:FedUp |
| | | WBPaper00035084:embryo_enriched_AIN-2_IP |
| | | WBPaper00035084:L2_enriched_AIN-2_IP |
| | | WBPaper00035084:L3_enriched_AIN-2_IP |
| | | WBPaper00035084:L4_enriched_AIN-2_IP |
| | | WBPaper00036286:Pattern_F |
| | | WBPaper00037113:Diazinon_16C_regulated |
| | | WBPaper00037147:heatshock_upregulated |
| | | WBPaper00040210:Chlorpyrifos_16C_regulated |
| | | WBPaper00040985:AIN-2_asynchronous_intestine |
| | | WBPaper00040985:AIN-2_asynchronous_muscle |
| | | WBPaper00041002:HF_11d_2.0mM_Down |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:cluster_83 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(41_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_MD |
| | | [cgc5767]:expression_class_MDE |
| | | [cgc5767]:expression_class_MD_pd(23_min) |
| | | [cgc5767]:expression_class_ME |
| | Interaction (26) |
| Map_info | Map | IV | Position | 4.91006 | Error | 0.00115 |
| | Positive | Positive_clone | C08F8 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00031309 |
| | WBPaper00038444 |
| | WBPaper00038491 |
| | WBPaper00055090 |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
