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WormBase Tree Display for Gene: WBGene00015116

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Name Class

WBGene00015116SMapS_parentSequenceB0286
IdentityVersion3
NameCGC_namepaic-1Person_evidenceWBPerson25639
Author_evidenceWendy Hanna-Rosed
Sequence_nameB0286.3
Molecular_nameB0286.3
B0286.3.1
CE03863
Other_namepacs-1
CELE_B0286.3Accession_evidenceNDBBX284602
Public_namepaic-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
205 Nov 2015 12:33:59WBPerson2970Name_changeCGC_namepacs-1
315 Jul 2019 14:29:07WBPerson1983Name_changeCGC_namepaic-1
Other_namepacs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpaic
Allele (48)
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (38)
Structured_descriptionAutomated_descriptionEnables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5419Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8587)
Molecular_infoCorresponding_CDSB0286.3
Corresponding_transcriptB0286.3.1
Other_sequence (104)
Associated_featureWBsf649998
WBsf665458
WBsf981185
WBsf222914
Experimental_infoRNAi_resultWBRNAi00038882Inferred_automaticallyRNAi_primary
WBRNAi00009674Inferred_automaticallyRNAi_primary
WBRNAi00072881Inferred_automaticallyRNAi_primary
WBRNAi00103145Inferred_automaticallyRNAi_primary
WBRNAi00028065Inferred_automaticallyRNAi_primary
Expr_patternExpr1014235
Expr1036460
Expr1143070
Microarray_results (18)
Expression_clusterWBPaper00028451:Abundant_spermatogenesis_enriched
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00033065:isp-1-1(qm150)_upregulated
WBPaper00036738:500uM_Heme_downregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038237:age-1_upregulated_intestine_rescue
WBPaper00038237:age-1_upregulated_neuron_rescue
WBPaper00038237:age-1_upregulated_nontransgenic
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044005:DAF-16_upregulated
WBPaper00044030:nhr-8(hd117)_downregulated
WBPaper00044128:daf-2(e1370)_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044760:somatic_specific
WBPaper00045390:ubc-9(RNAi)_upregulated
WBPaper00045401:N.parisii_64h_downregulated
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048923:Aging_regulated
WBPaper00048971:daf-16(mgDf50)_downregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049018:ham-3(RNAi)_upregulated
WBPaper00049217:DAF-16_upregulated
WBPaper00049290:rsks-1(sv31)_upregulated
WBPaper00049368:daf-2(e1370)_upregulated
WBPaper00049484:elt-2(RNAi)_downregulated_L4
WBPaper00049498:npr-1(ur89)_regulated_8
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00049905:Age_variant_expression
WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
WBPaper00049920:Glucose-Diet_upregulated_N2
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
WBPaper00050332:daf-16(RNAi)_downregulated
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050928:male-mating_downregulated
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051245:cytoplasm_specific
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051305:vit-2(ac3)_downregulated
WBPaper00051311:VGLN-1-interacting
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00051404:alg-2(ok304)_downregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053020:sid-3(ok973)_upregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(icb38)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053782:daf-2(RNAi)_oocyte_upregulated
WBPaper00053810:clk-1(qm30)_downregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053814:15C_upregulated_PY79
WBPaper00054192:cold-shock_downregulated
WBPaper00054872:egl-9(sa307)_downregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00055827:daf-2(e1370)_upregulated
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056090:hpx-2(dg047)_upregulated_E.faecalis
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056284:ints-1(RNAi)_upregulated
WBPaper00056443:DietaryRestriction_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056619:CEPsh_enriched
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:Cadmium_downregulated
WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058711:skn-1(lax188)_downregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058969:RIS_depleted
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_acr-2(n2420gf)_regulated
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059895:wounding_downregulated
WBPaper00059987:Wounding_downregulated
WBPaper00060014:set-2(zr2012)_upregulated
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060683:hlh-11(overexpression)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061106:endu-2(tm4977)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061274:microgravity_upregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:gst-26-pho-1_10767
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061651:Intestine_enriched
WBPaper00061651:Rectal_gland_enriched
WBPaper00061699:daf-18(ok480)_downregulated
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062440:crh-1(n3315)_upregulated
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
WBPaper00064005:starvation_upregulated_N2_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064315:mes-3(bn199)_downregulated_EGCs
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064716:paraquat_downregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00064728:cpl-1(W32AY35A)_upregulated
WBPaper00064769:him-17(me24)_upregulated
WBPaper00064789:Day3_vs_Day1_upregulated_neuron
WBPaper00064789:Day6_vs_Day1_upregulated_neuron
WBPaper00064841:tent-5(tm3504)_downregulated_protein
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065841:3_5
WBPaper00065841:30_0
WBPaper00065841:30_3
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065984:pals-17(syb3980)_downregulated
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066118:cyclobutrifluram_downregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4489_group_9
WBPaper00005124:progesterone_10-7M_regulated
WBPaper00025099:NI_specific
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00031060:2-deoxy-D-glucose_upregulated
WBPaper00031703:heme_responsive_8
WBPaper00032062:age_regulated_genes
WBPaper00034739:N2lessDR1350
WBPaper00034739:RIL17moreRIL14
WBPaper00034757:up_by_oxidative_stress
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00035873:osmotically_regulated
WBPaper00036286:Pattern_C
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00038304:octr-1_regulated
WBPaper00038462:aging_downregulated
WBPaper00040963:Q200_up
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
WBPaper00044091:Bpseudomallei_repressed_2h
WBPaper00044535:male_downregulated
WBPaper00045015:nhr-25(RNAi)_downregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00053236:daf-16(mgDF50)_regulated_Starved
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00057098:SiO2-nanoparticles_downregulated
[cgc5976]:class_1
[cgc6390]:Cluster_B
InteractionWBInteraction000143328
WBInteraction000155812
WBInteraction000155813
WBInteraction000192957
WBInteraction000324430
WBInteraction000327732
WBInteraction000351386
WBInteraction000358457
WBInteraction000360630
WBInteraction000375159
WBInteraction000422972
WBInteraction000440617
WBInteraction000450745
WBInteraction000505779
WBInteraction000505782
WBInteraction000505783
WBInteraction000505784
WBInteraction000505785
WBInteraction000505786
WBInteraction000511545
WBInteraction000511546
WBInteraction000511547
WBInteraction000511548
WBInteraction000545936
WBInteraction000545946
WBInteraction000545962
WBInteraction000545979
WBInteraction000545990
WBInteraction000545994
WBInteraction000545997
WBInteraction000546002
WBInteraction000546039
WBInteraction000546084
WBInteraction000546135
WBInteraction000546139
WBInteraction000546187
WBInteraction000546210
WBInteraction000546246
WBInteraction000546264
WBInteraction000546354
WBInteraction000546400
WBInteraction000546563
WBInteraction000546871
WBInteraction000546917
WBInteraction000560602
WBInteraction000563184
WBInteraction000567567
WBInteraction000578016
WBInteraction000580888
Map_infoMapIIPosition-4.75524
PositivePositive_cloneB0286Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00063700
WBPaper00064370
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
Previously in the pacs gene class
[200225 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-4.76524 )
MethodGene