WormBase Tree Display for Gene: WBGene00006794

WBGene00006794 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: unc-60 Person_evidence: WBPerson77
      Sequence_name: C38C3.5
      Molecular_name: C38C3.5
        C38C3.5.1
        CE20549
      Other_name: unc-66
        C38C3.f Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_C38C3.5 Accession_evidence: NDB BX284605
      Public_name: unc-60
    DB_info: Database: AceView gene 5B957
        WormQTL gene WBGene00006794
        WormFlux gene WBGene00006794
        NDB locus_tag CELE_C38C3.5
        Panther gene CAEEL|WormBase=WBGene00006794|UniProtKB=Q07750
          family PTHR11913
        NCBI gene 178640
        RefSeq protein NM_071026.11
        SwissProt UniProtAcc Q07749
        OMIM gene 601443
    Species: Caenorhabditis elegans
    History (2)
    Status: Live
  Gene_info (13)
  Disease_info: Potential_model: DOID:4948 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
      DOID:0110934 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1875)
      DOID:11457 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
  Molecular_info: Corresponding_CDS: C38C3.5
    Corresponding_CDS_history: C38C3.5a:wp264
      C38C3.5b:wp86
      C38C3.5b:wp249
      C38C3.5c:wp264
    Corresponding_transcript: C38C3.5.1
    Other_sequence (212)
    Associated_feature (19)
  Experimental_info: RNAi_result (17)
    Expr_pattern (11)
    Drives_construct: WBCnstr00019150
      WBCnstr00034145
    Construct_product: WBCnstr00015454
      WBCnstr00015473
      WBCnstr00015475
      WBCnstr00015476
      WBCnstr00015477
      WBCnstr00015478
      WBCnstr00019150
      WBCnstr00019151
      WBCnstr00019152
      WBCnstr00034145
    Antibody: WBAntibody00000222
      WBAntibody00000223
      WBAntibody00002955
    Microarray_results (24)
    Expression_cluster: WBPaper00028360:Phospho-Sulfo-Modified_proteins
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:up_in_alg-1
      WBPaper00032425:up_in_lin-35
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038289:oocyte_protein
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040755:LRRK2(wt)-Tau_vs_N2_downregulated
      WBPaper00040755:LRRK2(wt)-Tau_vs_Tau_upregulated
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00041257:irradiation_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046691:P1_enriched
      WBPaper00048810:CoQ-deficiency_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049626:UNC-75_target
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050599:nicotine(1mM)_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057136:yap-1(ys38)_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:mu_sph
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:gpb-1_3783-C48A7.2_22459
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064315:mes-3(bn199)_downregulated_PGCs
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:7_4
      WBPaper00065841:38_3
      WBPaper00065841:143_0
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_5
      cgc4386_cluster_5_4
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00032948:FedUp
      WBPaper00033099:organophosphorus_pesticide_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
    Interaction: WBInteraction000000035
      WBInteraction000001322
      WBInteraction000002986
      WBInteraction000003390
      WBInteraction000005335
      WBInteraction000005434
      WBInteraction000005825
      WBInteraction000007846
      WBInteraction000009105
      WBInteraction000009380
      WBInteraction000009539
      WBInteraction000009953
      WBInteraction000028725
      WBInteraction000031878
      WBInteraction000032654
      WBInteraction000033213
      WBInteraction000033460
      WBInteraction000033461
      WBInteraction000033596
      WBInteraction000033730
      WBInteraction000034026
      WBInteraction000034644
      WBInteraction000034931
      WBInteraction000035038
      WBInteraction000035143
      WBInteraction000035145
      WBInteraction000035724
      WBInteraction000035744
      WBInteraction000035949
      WBInteraction000035950
      WBInteraction000037208
      WBInteraction000038224
      WBInteraction000038240
      WBInteraction000038241
      WBInteraction000038264
      WBInteraction000038281
      WBInteraction000040059
      WBInteraction000040620
      WBInteraction000040684
      WBInteraction000040913
      WBInteraction000042516
      WBInteraction000042957
      WBInteraction000043164
      WBInteraction000044372
      WBInteraction000044406
      WBInteraction000044858
      WBInteraction000045584
      WBInteraction000046804
      WBInteraction000046805
      WBInteraction000047108
      WBInteraction000048533
      WBInteraction000049364
      WBInteraction000049590
      WBInteraction000049622
      WBInteraction000050403
      WBInteraction000103000
      WBInteraction000111398
      WBInteraction000115745
      WBInteraction000116305
      WBInteraction000126335
      WBInteraction000127462
      WBInteraction000127463
      WBInteraction000133383
      WBInteraction000133513
      WBInteraction000136233
      WBInteraction000137224
      WBInteraction000137225
      WBInteraction000137226
      WBInteraction000137227
      WBInteraction000148162
      WBInteraction000149054
      WBInteraction000150184
      WBInteraction000150185
      WBInteraction000150186
      WBInteraction000150187
      WBInteraction000150188
      WBInteraction000163048
      WBInteraction000166411
      WBInteraction000166412
      WBInteraction000174007
      WBInteraction000174008
      WBInteraction000175527
      WBInteraction000175528
      WBInteraction000177530
      WBInteraction000177820
      WBInteraction000181189
      WBInteraction000185458
      WBInteraction000188283
      WBInteraction000188285
      WBInteraction000188287
      WBInteraction000188291
      WBInteraction000188292
      WBInteraction000188293
      WBInteraction000188294
      WBInteraction000188295
      WBInteraction000188296
      WBInteraction000194595
      WBInteraction000200038
      WBInteraction000207386
      WBInteraction000211451
      WBInteraction000211453
      WBInteraction000222895
      WBInteraction000226955
      WBInteraction000241779
      WBInteraction000242502
      WBInteraction000246965
      WBInteraction000256150
      WBInteraction000257122
      WBInteraction000264404
      WBInteraction000266861
      WBInteraction000266862
      WBInteraction000266863
      WBInteraction000277124
      WBInteraction000282547
      WBInteraction000291742
      WBInteraction000296199
      WBInteraction000302612
      WBInteraction000306760
      WBInteraction000306761
      WBInteraction000312416
      WBInteraction000327129
      WBInteraction000331867
      WBInteraction000339614
      WBInteraction000354308
      WBInteraction000355465
      WBInteraction000361241
      WBInteraction000377810
      WBInteraction000381679
      WBInteraction000383461
      WBInteraction000387131
      WBInteraction000392653
      WBInteraction000393923
      WBInteraction000396863
      WBInteraction000400461
      WBInteraction000407929
      WBInteraction000413181
      WBInteraction000417433
      WBInteraction000417434
      WBInteraction000428033
      WBInteraction000428101
      WBInteraction000428218
      WBInteraction000430084
      WBInteraction000434664
      WBInteraction000434799
      WBInteraction000436791
      WBInteraction000444440
      WBInteraction000445482
      WBInteraction000456507
      WBInteraction000459005
      WBInteraction000465436
      WBInteraction000465562
      WBInteraction000469583
      WBInteraction000469766
      WBInteraction000473792
      WBInteraction000473793
      WBInteraction000475288
      WBInteraction000500377
      WBInteraction000500378
      WBInteraction000500379
      WBInteraction000501464
      WBInteraction000501690
      WBInteraction000502010
      WBInteraction000502344
      WBInteraction000503587
      WBInteraction000503588
      WBInteraction000518632
      WBInteraction000519059
      WBInteraction000519060
      WBInteraction000519073
      WBInteraction000519088
      WBInteraction000519089
      WBInteraction000519090
      WBInteraction000519166
      WBInteraction000520189
      WBInteraction000522767
      WBInteraction000522768
      WBInteraction000542002
      WBInteraction000542003
      WBInteraction000542004
      WBInteraction000542289
      WBInteraction000542290
      WBInteraction000542291
      WBInteraction000542460
      WBInteraction000542586
      WBInteraction000542700
      WBInteraction000547475
      WBInteraction000547476
      WBInteraction000549388
      WBInteraction000551456
      WBInteraction000552441
      WBInteraction000552972
      WBInteraction000554525
      WBInteraction000555010
      WBInteraction000560894
      WBInteraction000562987
      WBInteraction000564730
      WBInteraction000569401
      WBInteraction000572074
      WBInteraction000574180
      WBInteraction000574536
      WBInteraction000577805
      WBInteraction000580484
      WBInteraction000585609
    Anatomy_function: WBbtf0607
  Map_info: Map: V Position: -18.8768 Error: 0.017792
    Well_ordered
    Positive: Inside_rearr: sDf28
        rT1
      Positive_clone: C32E5
        C38C3 Inferred_automatically: From sequence, transcript, pseudogene data
        F53E2
    Mapping_data: 2_point (13)
      Multi_point (29)
      Pos_neg_data: 1793
        1799
        1805
        2166
        3092
        3257
        3096
        3105
        3582
        5182
    Landmark_gene
  Reference (119)
  Remark: [ Wakarchuck MF] dpy-18(e364)/eT1; unc-60(m35)/eT1 male was crossed to eT1(III;V); sEx9 [pRF4{rol-6(su1006)}+C32E5] hermaphrodite. F1 rollers segregated fertile Dpy non-Uncs among their progeny, indicating rescue of unc-60(m35).
  Method: Gene