WormBase Tree Display for Gene: WBGene00006534

WBGene00006534 SMap: S_parent: Sequence: ZK899
  Identity: Version: 1
    Name: CGC_name: tba-8
      Sequence_name: ZK899.4
      Molecular_name (3)
      Other_name: CELE_ZK899.4 Accession_evidence: NDB BX284606
      Public_name: tba-8
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tba
    Allele (53)
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (38)
    Paralog (16)
    Structured_description: Concise_description: tba-8 encodes a member of the alpha tubulin family with high similarity to the human tubulin alpha-6 chain; expressed in some neurons with occasional expression in the hypodermis. Paper_evidence: WBPaper00002319
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in germ line; posterior lateral ganglion; retrovesicular ganglion; seam cell; and ventral cord neurons. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK899.4
    Corresponding_CDS_history: ZK899.4:wp131
    Corresponding_transcript: ZK899.4.1
    Other_sequence: CJC11183_1
      EX914457.1
      Hbac_isotig06798
      MP00928
      JI211919.1
      CBC15796_1
      Dviv_isotig23553
      CJC15627_1
      HBC27446_1
    Associated_feature: WBsf237774
  Experimental_info: RNAi_result: WBRNAi00081670 Inferred_automatically: RNAi_primary
      WBRNAi00038495 Inferred_automatically: RNAi_primary
      WBRNAi00022225 Inferred_automatically: RNAi_primary
      WBRNAi00059818 Inferred_automatically: RNAi_primary
      WBRNAi00076901 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr45
      Expr1021495
      Expr1163249
      Expr2017315
      Expr2035450
    Drives_construct: WBCnstr00034319
    Construct_product: WBCnstr00034319
    Microarray_results (18)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044260:nicotinc-acid_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00046887:WNT-target
      WBPaper00048611:MnCl2_upregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:daf-16(mu86)_upregulated_neuron
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053771:down_by_skn-1(RNAi)_at_24h-NaCl
      WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055013:hmg-4(RNAi)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055226:adr-1(tm668)_upregulated
      WBPaper00055354:Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
      WBPaper00057347:nhr-14(tm1473)_downreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059426:Ag-nanoparticles_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060445:ikb-1(nr2027)_downregulated_L1
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061357:mett-10(ok2204)_upregulated_OP50
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:xbx-3-DH11.5_20397
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062056:lin-15B(n744)_downregulated
      WBPaper00062056:lin-15B(we23)_downregulated
      WBPaper00062056:lin-35(n745)_downregulated
      WBPaper00062056:lin-36(we31)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062347:blmp-1(tm548)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064201:SNA-1_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064841:tent-5(tm3504)_downregulated_protein
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065841:119_0
      WBPaper00065877:rege-1(imm070)_downregulated_PA14
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4489_group_21
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_G
      WBPaper00036383:ash-2_L3_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00041207:CE_dauer_down
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00053236:Starvation_regulated_N2
    Interaction: WBInteraction000114698
      WBInteraction000115832
      WBInteraction000116214
      WBInteraction000120175
      WBInteraction000127375
      WBInteraction000134216
      WBInteraction000135321
      WBInteraction000136046
      WBInteraction000137559
      WBInteraction000247866
      WBInteraction000269571
      WBInteraction000276669
      WBInteraction000303119
      WBInteraction000303650
      WBInteraction000314351
      WBInteraction000340834
      WBInteraction000340839
      WBInteraction000341052
      WBInteraction000344654
      WBInteraction000358197
      WBInteraction000361469
      WBInteraction000379415
      WBInteraction000402132
      WBInteraction000451828
      WBInteraction000451998
      WBInteraction000461418
      WBInteraction000466343
      WBInteraction000471144
      WBInteraction000471971
      WBInteraction000472358
      WBInteraction000560959
      WBInteraction000571863
  Map_info: Map: X Position: 1.26204 Error: 0.021917
    Positive: Positive_clone: ZK899 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042741
    WBPaper00045213
    WBPaper00049828
    WBPaper00055090
    WBPaper00056909
    WBPaper00059214
  Remark: Sequence connection from [Gogonea CB, Siddiqui SS]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene