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WormBase Tree Display for Gene: WBGene00000484

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Name Class

WBGene00000484EvidenceCGC_data_submission
SMapS_parentSequenceF38G1
IdentityVersion1
NameCGC_nameche-2Person_evidenceWBPerson261
Sequence_nameF38G1.1
Molecular_nameF38G1.1
F38G1.1.1
CE25876
Other_nameCELE_F38G1.1Accession_evidenceNDBBX284606
Public_nameche-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classche
Reference_alleleWBVar00143695
Allele (93)
Legacy_informatione1033 : non-chemotactic to sodium ion slightly small defective osmotic avoidance defective dauer formation males impotent; no FITC uptake; ciliated neurons have abnormal stunted ultrastructure. ES2 ME0. NA1.
See also e1033
[C.elegansII] e1033 : non-chemotactic to sodium ion; slightly small; defective osmotic avoidance; defective dauer formation; males impotent; Dyf (no FITC uptake); ciliated neurons have abnormal stunted ultrastructure. ES2. ME0.OA5: m127, mn330mut, mn395 etc. [Lewis and Hodgkin 1977; Starich et al. 1995; DR; SP; NJ]
StrainWBStrain00030520
WBStrain00030521
WBStrain00004231
WBStrain00006208
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (39)
Structured_descriptionConcise_descriptionche-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays.Paper_evidenceWBPaper00001482
WBPaper00001786
WBPaper00002033
WBPaper00003761
WBPaper00003977
WBPaper00004692
WBPaper00005596
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionInvolved in several processes, including dauer larval development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of locomotion involved in locomotory behavior. Located in ciliary basal body and non-motile cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is an ortholog of human IFT80 (intraflagellar transport 80).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS292 version of WormBase
Date_last_updated24 Apr 2024 00:00:00
Disease_infoPotential_modelDOID:0110086Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:29262)
Molecular_infoCorresponding_CDSF38G1.1
Corresponding_transcriptF38G1.1.1
Other_sequenceAcan_isotig12713
JI226764.1
Associated_featureWBsf042305
WBsf647785
WBsf1003791
WBsf235268
Experimental_infoRNAi_resultWBRNAi00014580Inferred_automaticallyRNAi_primary
WBRNAi00068042Inferred_automaticallyRNAi_primary
WBRNAi00067404Inferred_automaticallyRNAi_primary
WBRNAi00067940Inferred_automaticallyRNAi_primary
WBRNAi00046733Inferred_automaticallyRNAi_primary
Expr_patternExpr1157
Expr10123
Expr1024294
Expr1030285
Expr1150609
Expr2009965
Expr2028205
Drives_construct (17)
Construct_product (11)
Microarray_resultsSMD_F38G1.1
189244_at
A_12_P105035
Aff_F38G1.1
GPL13394_WBGene00000484
GPL13914_F38G1.1
GPL14144_F38G1.1_2007-2066_0.940_1_C
GPL14144_F38G1.1_719-778_0.840_54_B
GPL14144_F38G1.1_939-998_0.853_46_A
GPL19516_CGZ0020576
GPL19516_CGZ0020577
GPL21109_F38G1.1.1
GPL3518_CE25876
GPL8304_CE_WBGene00000484_A
GPL8304_CE_WBGene00000484_B
GPL8673_F38G1_1P01007
GPL8673_F38G1_1P01369
GPL8673_F38G1_1P02201
GPL9450_F38G1.1
cea2.c.44647
Expression_clusterWBPaper00032031:DConiospora_downregulated_OligoArray_24h
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_larva_enriched
WBPaper00037950:all-neurons_larva_SelectivelyEnriched
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:BAG-neuron_embryo_enriched
WBPaper00037950:BAG-neuron_embryo_SelectivelyEnriched
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_CoreEnriched
WBPaper00037950:dopaminergic-neurons_embryo_enriched
WBPaper00037950:dopaminergic-neurons_embryo_SelectivelyEnriched
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00045390:tunicamycin_downregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00050231:male_enriched
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055226:ADR-2_target_N2
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056284:ints-11(RNAi)_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058691:set-2(bn129)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059231:alh-6(lax105)_L4_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060014:set-2(zr2012)_downregulated
WBPaper00060526:plp-1(ok2155)_downregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060909:atfs-1(et18)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ADE
WBPaper00061340:ADF
WBPaper00061340:ADF_AWB
WBPaper00061340:ASE
WBPaper00061340:ASG
WBPaper00061340:ASG_AWA
WBPaper00061340:ASI_parent
WBPaper00061340:ASJ
WBPaper00061340:ASK
WBPaper00061340:ASK_parent
WBPaper00061340:AUA
WBPaper00061340:AWB
WBPaper00061340:AWC
WBPaper00061340:BAG
WBPaper00061340:CEP
WBPaper00061340:IL1
WBPaper00061340:IL1_parent
WBPaper00061340:IL2
WBPaper00061340:Neuroblast_ADE_ADA
WBPaper00061340:Neuroblast_ASJ_AUA
WBPaper00061340:Neuroblast_HSN_PHB
WBPaper00061340:Neuroblast_URX_CEPDx
WBPaper00061340:OLL_parent
WBPaper00061340:OLQ
WBPaper00061340:OLQ_parent
WBPaper00061340:URX
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061527:rab-28-jbts-14_9542
WBPaper00061853:osm-3(dh441)_downregulated
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062056:efl-1(se1)_upregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064721:fasn-1(g14)_downregulated_starved
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065158:AFD_enriched
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065841:25_0
WBPaper00065841:25_1
WBPaper00065841:36_2
WBPaper00065841:36_3
WBPaper00065841:39_0
WBPaper00065841:39_1
WBPaper00065841:39_2
WBPaper00065841:39_3
WBPaper00065841:44_1
WBPaper00065841:47_0
WBPaper00065841:100_0
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066485:ogt-1_upregulated_neuron
cgc4489_group_13
WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00030985:Enterococcus_faecalis_upregulated
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00036130:mir-243_up_regulated
WBPaper00039866:ClassComp_daf-19_downregulated
WBPaper00039866:SAM_daf-19_downregulated
WBPaper00040210:Diazinon_24C_regulated
WBPaper00045673:colistin_upregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
WBPaper00053550:daf-19(m86)_downregulated_L1
WBPaper00056330:mrps-5(RNAi)_upregulated
InteractionWBInteraction000001469
WBInteraction000001931
WBInteraction000001932
WBInteraction000005618
WBInteraction000006858
WBInteraction000007394
WBInteraction000007496
WBInteraction000028616
WBInteraction000029736
WBInteraction000029761
WBInteraction000126383
WBInteraction000126436
WBInteraction000126492
WBInteraction000126538
WBInteraction000127259
WBInteraction000134524
WBInteraction000142018
WBInteraction000142019
WBInteraction000149156
WBInteraction000161296
WBInteraction000161297
WBInteraction000161302
WBInteraction000165553
WBInteraction000165554
WBInteraction000165634
WBInteraction000179623
WBInteraction000185229
WBInteraction000191513
WBInteraction000191517
WBInteraction000200676
WBInteraction000202355
WBInteraction000220159
WBInteraction000246802
WBInteraction000249613
WBInteraction000253430
WBInteraction000259820
WBInteraction000261683
WBInteraction000264589
WBInteraction000265241
WBInteraction000270633
WBInteraction000277897
WBInteraction000300122
WBInteraction000300572
WBInteraction000302995
WBInteraction000312054
WBInteraction000321563
WBInteraction000339311
WBInteraction000342201
WBInteraction000345929
WBInteraction000358716
WBInteraction000361384
WBInteraction000365668
WBInteraction000366309
WBInteraction000371544
WBInteraction000386317
WBInteraction000388887
WBInteraction000389746
WBInteraction000390220
WBInteraction000393045
WBInteraction000393937
WBInteraction000400207
WBInteraction000402619
WBInteraction000418104
WBInteraction000421031
WBInteraction000444315
WBInteraction000444665
WBInteraction000446841
WBInteraction000447311
WBInteraction000454122
WBInteraction000462579
WBInteraction000475059
WBInteraction000500288
WBInteraction000500291
WBInteraction000500292
WBInteraction000500293
WBInteraction000500294
WBInteraction000518966
WBInteraction000520975
WBInteraction000542904
WBInteraction000542917
WBInteraction000556041
Map_infoMapXPosition-19.7593Error0.046333
Well_ordered
PositivePositive_cloneF38G1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point3385
Multi_point1213
1585
1856
2320
2431
2432
4432
Pos_neg_data5455
5461
5466
5470
5474
5478
5482
5486
5490
5494
Reference (127)
RemarkSequence connection from [Fujiwara M, Katsura I]
MethodGene