Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00000961

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00000961SMapS_parentSequenceT21B6
IdentityVersion1
NameCGC_namedgn-1Person_evidenceWBPerson345
Sequence_nameT21B6.1
Molecular_nameT21B6.1
T21B6.1.1
CE03679
T21B6.1.2
Other_nameCELE_T21B6.1Accession_evidenceNDBBX284606
Public_namedgn-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdgn
Allele (109)
Possibly_affected_byWBVar02152924
StrainWBStrain00005032
WBStrain00005038
WBStrain00005039
WBStrain00047387
WBStrain00053443
RNASeq_FPKM (74)
GO_annotation00075877
00075878
00075879
00075880
00075881
00075882
00075883
00075884
00075885
00075886
00075887
00075888
00075889
00075890
00075891
00075892
00075893
00075894
00075895
00075896
00075897
00075898
00075899
00108086
00108087
00108088
Ortholog (31)
ParalogWBGene00018943Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiondgn-1 encodes dystroglycan, a basement membrane component.Paper_evidenceWBPaper00027321
Curator_confirmedWBPerson1843
Date_last_updated26 Jan 2012 00:00:00
Automated_descriptionPredicted to enable laminin binding activity. Involved in anatomical structure morphogenesis; inductive cell migration; and positive regulation of locomotion. Located in basal plasma membrane. Expressed in several structures, including ALM; PVP; e2; gonad; and lumbar ganglion. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; Fukuyama congenital muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; bronchopulmonary dysplasia; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is an ortholog of human DAG1 (dystroglycan 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110278Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0050559Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:11723Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:3429Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0110293Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:11650Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
DOID:0111232Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2666)
Molecular_infoCorresponding_CDST21B6.1
Corresponding_transcriptT21B6.1.1
T21B6.1.2
Other_sequence (16)
Associated_feature (19)
Experimental_infoRNAi_resultWBRNAi00035744Inferred_automaticallyRNAi_primary
WBRNAi00018957Inferred_automaticallyRNAi_primary
WBRNAi00110305Inferred_automaticallyRNAi_primary
WBRNAi00053703Inferred_automaticallyRNAi_primary
WBRNAi00092897Inferred_automaticallyRNAi_primary
Expr_patternExpr4218
Expr4219
Expr9931
Expr12559
Expr14845
Expr1022924
Expr1030596
Expr1157255
Expr2010868
Expr2029106
Drives_constructWBCnstr00011834
WBCnstr00014941
WBCnstr00015884
WBCnstr00037177
WBCnstr00038162
Construct_productWBCnstr00011834
WBCnstr00015884
WBCnstr00016598
WBCnstr00037177
WBCnstr00038162
AntibodyWBAntibody00001077
WBAntibody00001078
Microarray_results (28)
Expression_clusterWBPaper00030922:glycosylated_protein
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00044260:1-methylnicotinamide_downregulated
WBPaper00044260:nicotic-acid_downregulated
WBPaper00044426:rotenone_24h_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045316:prg-1_upregulated_L2
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Spermatogenic
WBPaper00045571:germline-ablation_upregulated
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00049954:BPS_upregulated
WBPaper00050015:ifg-1(RNAi)_upregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050344:PLM-neuron_enriched
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00051555:atm-1(gk186)_regulated_protein
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053814:15C_downregulated_OP50
WBPaper00053814:15C_downregulated_PY79
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00055049:S.gordonii_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Rifampicin_upregulated
WBPaper00055565:AVK_enriched
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056167:ifo-1(kc2)_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056619:CEPsh_enriched
WBPaper00056826:SGP_biased
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00057140:pptr-1(tm3103)_upregulated
WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058969:RIS_depleted
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059471:EGL-43_interacting
WBPaper00059763:neuron_expressed
WBPaper00059895:wounding_upregulated
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061274:microgravity_upregulated
WBPaper00061340:ADA_ADE_grandparent
WBPaper00061340:ALN
WBPaper00061340:ASG_AWA
WBPaper00061340:CAN
WBPaper00061340:Ciliated_amphid_neuron
WBPaper00061340:DA
WBPaper00061340:DB
WBPaper00061340:DVA
WBPaper00061340:DVC_parent
WBPaper00061340:I1_parent
WBPaper00061340:Neuroblast_ADF_AWB
WBPaper00061340:Neuroblast_AIZ_FLP_RMG
WBPaper00061340:Neuroblast_ALM_BDU
WBPaper00061340:Neuroblast_ASG_AWA
WBPaper00061340:Neuroblast_ASH_RIB
WBPaper00061340:Neuroblast_AVG_RIR
WBPaper00061340:Neuroblast_PVC_LUA
WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
WBPaper00061340:Parent_of_exc_gland_AVK
WBPaper00061340:PLM_ALN_grandparent
WBPaper00061340:PVP
WBPaper00061340:PVQ_parent
WBPaper00061340:RIM_parent
WBPaper00061340:Z1_Z4
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061527:ldb-1_2877-scd-1_3086
WBPaper00061527:pkn-1_20439-tbc-12_11015
WBPaper00061651:Distal_tip_cell_enriched
WBPaper00061902:camt-1(ok515)_regulated_AFD
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062520:qui-1(db104)_downregulated
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064716:paraquat_upregulated
WBPaper00065086:N2_N.ironsii_regulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065258:anchor-cell_enriched
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065835:Day11_vs_Day1_upregulated
WBPaper00065841:1_2
WBPaper00065841:11_0
WBPaper00065841:11_2
WBPaper00065841:11_3
WBPaper00065841:31_0
WBPaper00065841:50_0
WBPaper00065841:60_0
WBPaper00065841:62_0
WBPaper00065841:67_0
WBPaper00065841:74_0
WBPaper00065841:145_0
WBPaper00066085:hda-3(ok1991)_downregulated
cgc4386_cluster_6_3
WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
WBPaper00025032:cluster_16
WBPaper00025032:cluster_93
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00029437:dcr-1_upregulated
WBPaper00031832:slr-2_regulated
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00036123:Cadmium_regulated
WBPaper00036286:Pattern_I
WBPaper00040210:Diazinon_24C_regulated
WBPaper00040876:mir-35_upregulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00041002:HQ_3d_0.2mM_Down
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00047070:N2_starvation_downregulated
[cgc5767]:cluster_15
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(101_min)
[cgc5767]:expression_class_E_pi(122_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(101_min)
[cgc5767]:expression_class_SE_pi(122_min)
Interaction (32)
Map_infoMapXPosition2.70681Error0.005584
PositivePositive_cloneT21B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (23)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene