WormBase Tree Display for Gene: WBGene00001165
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WBGene00001165 | SMap | S_parent | Sequence | F56A11 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | efn-4 | Person_evidence | WBPerson893 | |||||
Sequence_name | F56A11.3 | ||||||||
Molecular_name | F56A11.3 | ||||||||
F56A11.3.1 | |||||||||
CE29503 | |||||||||
Other_name | mab-26 | ||||||||
CELE_F56A11.3 | Accession_evidence | NDB | BX284604 | ||||||
Public_name | efn-4 | ||||||||
DB_info | Database | AceView | gene | 4B319 | |||||
WormQTL | gene | WBGene00001165 | |||||||
SignaLink | protein | WBGene00001165 | |||||||
WormFlux | gene | WBGene00001165 | |||||||
NDB | locus_tag | CELE_F56A11.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001165|UniProtKB=O44516 | |||||||
family | PTHR11304 | ||||||||
NCBI | gene | 176882 | |||||||
RefSeq | protein | NM_067546.6 | |||||||
SwissProt | UniProtAcc | O44516 | |||||||
UniProt_GCRP | UniProtAcc | O44516 | |||||||
OMIM | gene | 300035 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | efn | ||||||||
Allele (170) | |||||||||
Legacy_information | [C.elegansII] bx80sd : fusions among all rays; also head, body and (especially) tail deformities; bx80/+ impenetrant R4 to R3 transformation. [Chow and Emmons 1994; EM] | ||||||||
Strain | WBStrain00005372 | ||||||||
WBStrain00007176 | |||||||||
WBStrain00049265 | |||||||||
WBStrain00049276 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (33) | |||||||||
Ortholog (50) | |||||||||
Paralog | WBGene00001163 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001164 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00006869 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | efn-4 encodes a divergent member of the ephrin family of ligands; efn-4 is required for neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; EFN-4 can interact weakly with VAB-1 in vitro; EFN-4 is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure. | Paper_evidence | WBPaper00003865 | |||||
WBPaper00005631 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 23 Jul 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable ephrin receptor binding activity. Involved in several processes, including embryonic morphogenesis; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in axon and neuronal cell body. Expressed in several structures, including CAN; epithelial cell; ganglia; intestinal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:1934 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||
DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
DOID:14737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||||
Molecular_info | Corresponding_CDS | F56A11.3 | |||||||
Corresponding_transcript | F56A11.3.1 | ||||||||
Other_sequence | CR11929 | ||||||||
TS00903 | |||||||||
TSC03402_1 | |||||||||
CRC05251_1 | |||||||||
CBC06448_1 | |||||||||
CR02130 | |||||||||
Associated_feature (22) | |||||||||
Experimental_info | RNAi_result | WBRNAi00111800 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00067312 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00086136 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00067361 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00064650 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048574 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015760 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (11) | |||||||||
Drives_construct | WBCnstr00000722 | ||||||||
WBCnstr00000723 | |||||||||
WBCnstr00006419 | |||||||||
WBCnstr00011024 | |||||||||
WBCnstr00037053 | |||||||||
WBCnstr00042431 | |||||||||
WBCnstr00042437 | |||||||||
Construct_product | WBCnstr00006419 | ||||||||
WBCnstr00021468 | |||||||||
WBCnstr00021469 | |||||||||
WBCnstr00021470 | |||||||||
WBCnstr00021472 | |||||||||
WBCnstr00021473 | |||||||||
WBCnstr00021477 | |||||||||
WBCnstr00022268 | |||||||||
WBCnstr00037053 | |||||||||
Antibody | WBAntibody00000596 | ||||||||
Microarray_results (21) | |||||||||
Expression_cluster (158) | |||||||||
Interaction | WBInteraction000000251 | ||||||||
WBInteraction000002082 | |||||||||
WBInteraction000002815 | |||||||||
WBInteraction000002816 | |||||||||
WBInteraction000002817 | |||||||||
WBInteraction000002819 | |||||||||
WBInteraction000004052 | |||||||||
WBInteraction000004053 | |||||||||
WBInteraction000004054 | |||||||||
WBInteraction000004055 | |||||||||
WBInteraction000004843 | |||||||||
WBInteraction000004844 | |||||||||
WBInteraction000005103 | |||||||||
WBInteraction000005440 | |||||||||
WBInteraction000005461 | |||||||||
WBInteraction000005464 | |||||||||
WBInteraction000006177 | |||||||||
WBInteraction000006766 | |||||||||
WBInteraction000006815 | |||||||||
WBInteraction000008780 | |||||||||
WBInteraction000008781 | |||||||||
WBInteraction000008782 | |||||||||
WBInteraction000008784 | |||||||||
WBInteraction000028617 | |||||||||
WBInteraction000029331 | |||||||||
WBInteraction000029695 | |||||||||
WBInteraction000029696 | |||||||||
WBInteraction000029748 | |||||||||
WBInteraction000030421 | |||||||||
WBInteraction000030422 | |||||||||
WBInteraction000030423 | |||||||||
WBInteraction000126392 | |||||||||
WBInteraction000136827 | |||||||||
WBInteraction000140842 | |||||||||
WBInteraction000140843 | |||||||||
WBInteraction000140844 | |||||||||
WBInteraction000140891 | |||||||||
WBInteraction000153201 | |||||||||
WBInteraction000165709 | |||||||||
WBInteraction000165721 | |||||||||
WBInteraction000166032 | |||||||||
WBInteraction000166248 | |||||||||
WBInteraction000166451 | |||||||||
WBInteraction000268413 | |||||||||
WBInteraction000322441 | |||||||||
WBInteraction000356890 | |||||||||
WBInteraction000366574 | |||||||||
WBInteraction000367858 | |||||||||
WBInteraction000369120 | |||||||||
WBInteraction000371302 | |||||||||
WBInteraction000392352 | |||||||||
WBInteraction000392531 | |||||||||
WBInteraction000417475 | |||||||||
WBInteraction000442425 | |||||||||
WBInteraction000446247 | |||||||||
WBInteraction000459007 | |||||||||
WBInteraction000541296 | |||||||||
WBInteraction000553813 | |||||||||
WBInteraction000556399 | |||||||||
WBInteraction000560778 | |||||||||
WBInteraction000560779 | |||||||||
WBInteraction000560780 | |||||||||
WBInteraction000560781 | |||||||||
WBProcess | WBbiopr:00000025 | ||||||||
Map_info | Map | IV | Position | -25.7615 | Error | 0.138637 | |||
Positive | Positive_clone | F56A11 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 3132 | |||||||
4992 | |||||||||
5641 | |||||||||
Reference (44) | |||||||||
Method | Gene |