WormBase Tree Display for Gene: WBGene00004492

WBGene00004492 SMap: S_parent: Sequence: F28D1
  Identity: Version: 1
    Name: CGC_name: rps-23
      Sequence_name: F28D1.7
      Molecular_name: F28D1.7a
        F28D1.7a.1
        CE05747
        F28D1.7b
      Other_name: CELE_F28D1.7 Accession_evidence: NDB BX284604
      Public_name: rps-23
    DB_info: Database: AceView gene 4N154
        WormQTL gene WBGene00004492
        WormFlux gene WBGene00004492
        NDB locus_tag CELE_F28D1.7
        Panther gene CAEEL|WormBase=WBGene00004492|UniProtKB=Q19877
          family PTHR11652
        NCBI gene 178188
        RefSeq protein NR_131618.1
            NM_069964.9
        SwissProt UniProtAcc Q19877
        UniProt_GCRP UniProtAcc Q19877
        OMIM gene 603683
        RNAcentral URSid URS000077351A
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rps
    Allele (18)
    Legacy_information: Orthologous to yeast (S.cerevisiae) ribosomal protein rps23 using blastP
    Strain: WBStrain00001593
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (40)
    Paralog: WBGene00011391 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: rps-23 encodes a small ribosomal subunit S23 protein; by homology, RPS-23 is predicted to function in protein biosynthesis; in C. elegans, RPS-23 activity is required for germline development, vulval morphogenesis, and the overall health of the animal. Paper_evidence: WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit and polysomal ribosome. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Is an ortholog of human RPS23 (ribosomal protein S23). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070415 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10410)
  Molecular_info: Corresponding_CDS: F28D1.7a
    Corresponding_transcript: F28D1.7b
      F28D1.7a.1
    Other_sequence (360)
    Associated_feature: WBsf652292
      WBsf652293
      WBsf981835
      WBsf998102
      WBsf998103
      WBsf231013
      WBsf231014
      WBsf231015
  Experimental_info: RNAi_result (14)
    Expr_pattern: Chronogram525
      Expr5902
      Expr1028388
      Expr1032295
      Expr1149739
      Expr2015518
      Expr2033753
    Drives_construct: WBCnstr00002433
      WBCnstr00035444
    Construct_product: WBCnstr00035444
    Microarray_results (21)
    Expression_cluster: WBPaper00024704:Soluble_protein
      WBPaper00029359_1197
      WBPaper00029359_1225
      WBPaper00029359_1291
      WBPaper00029359_1367
      WBPaper00029359_1483
      WBPaper00029359_1494
      WBPaper00029359_1546
      WBPaper00029359_1561
      WBPaper00029359_1692
      WBPaper00032528:L3_enriched
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038289:oocyte_protein
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040446:insoluble_protein
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00043951:Nascent-polypeptide-associated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046303:P.aeruginosa_upregulated_protein
      WBPaper00046691:P1_enriched
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00055013:HMG-4_interacting_protein
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00059254:PRG-1_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060908:TEBP-1_interacting
      WBPaper00060908:TEBP-2_interacting
      WBPaper00061340:Excretory_cell
      WBPaper00061340:M_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061393:C.albicans_regulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:rps-14_21270-rps-11_20714
      WBPaper00061651:ADA_enriched
      WBPaper00061651:CAN_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:Excretory_gland_cell_enriched
      WBPaper00061651:Germline_enriched
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:M2_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062143:PQN-59_interacting
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064163:ZNFX-1_interacting_young-adult
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064789:Day6_vs_Day1_downregulated_neuron
      WBPaper00064789:Day9_vs_Day1_downregulated_neuron
      WBPaper00064789:Day12_vs_Day1_downregulated_neuron
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      cgc4489_group_3
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (223)
  Map_info: Map: IV Position: 5.90161
    Positive: Positive_clone: F28D1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024230
    WBPaper00033166
    WBPaper00035215
    WBPaper00038491
    WBPaper00040293
    WBPaper00049828
    WBPaper00055090
    WBPaper00061547
    WBPaper00062338
    WBPaper00065988
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene