WormBase Tree Display for Gene: WBGene00003795

WBGene00003795 SMap: S_parent: Sequence: F59A2
  Identity: Version: 1
    Name: CGC_name: npp-9 Person_evidence: WBPerson1780
      Sequence_name: F59A2.1
      Molecular_name: F59A2.1a
        F59A2.1a.1
        CE17939
        F59A2.1b
        CE33525
        F59A2.1a.2
        F59A2.1b.1
      Other_name: Nup358 Paper_evidence: WBPaper00026834
        CELE_F59A2.1 Accession_evidence: NDB BX284603
      Public_name: npp-9
    DB_info: Database: AceView gene 3E490
        WormQTL gene WBGene00003795
        WormFlux gene WBGene00003795
        NDB locus_tag CELE_F59A2.1
        Panther gene CAEEL|WormBase=WBGene00003795|UniProtKB=Q86G90
          family PTHR23138
        NCBI gene 175443
        RefSeq protein NM_001384054.1
            NM_001384053.2
        TREEFAM TREEFAM_ID TF314797
        TrEMBL UniProtAcc Q86G90
            Q21021
        UniProt_GCRP UniProtAcc Q86G90
        OMIM gene 601181
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: npp
    Allele (66)
    Possibly_affected_by: WBVar02153243
    Strain: WBStrain00037569
      WBStrain00050853
      WBStrain00054781
    RNASeq_FPKM (74)
    GO_annotation: 00070018
      00070019
      00070020
      00070021
      00070022
      00083277
      00083278
      00083279
      00083280
      00111816
    Ortholog (41)
    Paralog: WBGene00003802 Caenorhabditis elegans From_analysis: Panther
      WBGene00004306 Caenorhabditis elegans From_analysis (2)
    Structured_description: Automated_description: Predicted to enable metal ion binding activity. Predicted to contribute to GTPase activator activity. Involved in embryo development and nucleus organization. Part of nuclear pore. Human ortholog(s) of this gene implicated in brain disease; inflammatory myofibroblastic tumor; and multiple myeloma. Is an ortholog of human RANBP2 (RAN binding protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050905 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9848)
      DOID:936 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9848)
      DOID:9538 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9848)
  Molecular_info: Corresponding_CDS: F59A2.1a
      F59A2.1b
    Corresponding_transcript: F59A2.1a.1
      F59A2.1a.2
      F59A2.1b.1
    Other_sequence (54)
    Associated_feature: WBsf650902
      WBsf650903
      WBsf650904
      WBsf666638
      WBsf981431
      WBsf991755
      WBsf226342
      WBsf226343
      WBsf226344
  Experimental_info: RNAi_result (39)
    Expr_pattern: Expr9022
      Expr1014944
      Expr1031781
      Expr1152834
      Expr2014394
      Expr2032635
    Construct_product: WBCnstr00006023
      WBCnstr00009708
      WBCnstr00009709
      WBCnstr00013679
      WBCnstr00022447
      WBCnstr00042030
    Antibody: WBAntibody00002131
    Microarray_results (28)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00035269:cde-1_regulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037946:MAB-5_interacting
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_downregulated
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051265:F1_morc-1(tm6048)_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062103:neuron_enriched
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062123:GLH-1_interacting
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_4_3
      cgc4489_group_2
      cgc4489_group_3
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025032:cluster_1
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026629:L4_hermaphrodite_enriched
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030985:Serratia_marcesens_upregulated
      WBPaper00032948:FedUp
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_3h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
      [cgc6390]:oogenesis-enriched
    Interaction (362)
  Map_info: Map: III Position: -6.97528 Error: 0.012592
    Positive: Positive_clone: F59A2 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Sequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene