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WormBase Tree Display for Gene: WBGene00019636

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Name Class

WBGene00019636SMapS_parentSequenceK10F12
IdentityVersion2
NameCGC_namegsto-3
Sequence_nameK10F12.4
Molecular_nameK10F12.4a
K10F12.4a.1
CE12092
K10F12.4b
CE31038
K10F12.4b.1
Other_nameCELE_K10F12.4Accession_evidenceNDBBX284603
Public_namegsto-3
DB_infoDatabaseAceViewgene3A986
WormQTLgeneWBGene00019636
WormFluxgeneWBGene00019636
NDBlocus_tagCELE_K10F12.4
PanthergeneCAEEL|WormBase=WBGene00019636|UniProtKB=O17234
familyPTHR43968
NCBIgene175196
RefSeqproteinNM_001393255.1
NM_171061.1
TREEFAMTREEFAM_IDTF105325
TrEMBLUniProtAccO17234
Q8IA74
UniProt_GCRPUniProtAccO17234
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
230 Oct 2007 09:50:31WBPerson2970Name_changeCGC_namegsto-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgsto
AlleleWBVar01500082
WBVar01768446
WBVar01768447
WBVar01768448
WBVar01768449
WBVar01768450
WBVar01254550
WBVar01768451
WBVar01768452
WBVar01254552
WBVar01768453
WBVar02029932
WBVar02029933
WBVar02029934
WBVar02012589
WBVar01498832
WBVar01902966
WBVar01902967
WBVar01902968
WBVar01478984
WBVar02069384
WBVar01399767
WBVar01399778
WBVar01399789
WBVar01399800
WBVar01399811
WBVar00796654
WBVar00796655
WBVar00796656
WBVar00796657
WBVar00796658
WBVar00796659
WBVar00387748
WBVar00796660
WBVar00796661
WBVar00387749
WBVar00387750
WBVar00796662
WBVar01951061
WBVar00796663
WBVar00387751
WBVar00796664
WBVar00796665
WBVar00796666
WBVar00796667
WBVar01564051
WBVar00796668
WBVar00796669
WBVar00796670
WBVar00796671
WBVar00796672
WBVar00796673
WBVar00796674
WBVar00796675
WBVar00796676
WBVar00796677
WBVar00796678
WBVar00796679
WBVar00796680
WBVar00796681
WBVar01499668
WBVar01700343
WBVar00029903
WBVar02053006
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (38)
ParalogWBGene00001792Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00015337Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016204Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00043097Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001365Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001371Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001790Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001791Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008920Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021817Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionK10F12.4 encodes, by alternative splicing, one isoform of a putative omega-class glutathione transferase (GST; EC 2.5.1.18) which, like its paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; other K10F12.4 paralogs include GST-44 and C02D5.3; K10F12.4 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00031042
WBPaper00031083
Curator_confirmedWBPerson567
Date_last_updated16 Oct 2007 00:00:00
Automated_descriptionPredicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
DOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23064)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
Molecular_infoCorresponding_CDSK10F12.4a
K10F12.4b
Corresponding_transcriptK10F12.4a.1
K10F12.4b.1
Other_sequence (28)
Associated_feature (2)
Experimental_infoRNAi_resultWBRNAi00050549Inferred_automaticallyRNAi_primary
WBRNAi00006697Inferred_automaticallyRNAi_primary
WBRNAi00016984Inferred_automaticallyRNAi_primary
WBRNAi00034265Inferred_automaticallyRNAi_primary
Expr_patternExpr1028100
Expr1038480
Expr1154252
Expr2012338
Expr2030575
Microarray_results (22)
Expression_cluster (128)
Interaction (55)
Map_infoMapIIIPosition-26.8824Error0.003615
PositivePositive_cloneK10F12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene