WormBase Tree Display for Gene: WBGene00019327

WBGene00019327 SMap: S_parent: Sequence: K02F3
  Identity: Version: 2
    Name: CGC_name: zip-2 Person_evidence: WBPerson1997
            WBPerson460
      Sequence_name: K02F3.4
      Molecular_name: K02F3.4
        K02F3.4.1
        CE23848
        K02F3.4.2
        K02F3.4.3
      Other_name: CELE_K02F3.4 Accession_evidence: NDB BX284603
      Public_name: zip-2
    DB_info: Database: AceView gene 3B453
        WormQTL gene WBGene00019327
        WormFlux gene WBGene00019327
        NDB locus_tag CELE_K02F3.4
        Panther gene CAEEL|WormBase=WBGene00019327|UniProtKB=Q21148
          family PTHR23334
        NCBI gene 175240
        RefSeq protein NM_001384015.2
        SwissProt UniProtAcc Q21148
        TREEFAM TREEFAM_ID TF317134
        UniProt_GCRP UniProtAcc Q21148
    Species: Caenorhabditis elegans
    History: Version_change (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: zip
    Allele: WBVar00007026
      WBVar00007031
      WBVar01500082
      WBVar00799690
      WBVar00799691
      WBVar00799692
      WBVar00799693
      WBVar00799694
      WBVar00799695
      WBVar00799696
      WBVar00799697
      WBVar00799698
      WBVar00799699
      WBVar00799700
      WBVar00799701
      WBVar00799702
      WBVar00799703
      WBVar00799704
      WBVar01499552
      WBVar00799705
      WBVar00799706
      WBVar00799707
      WBVar00799708
      WBVar00799709
      WBVar01498832
      WBVar01769214
      WBVar01903512
      WBVar01903513
      WBVar01903514
      WBVar01903515
      WBVar01951235
      WBVar01951236
      WBVar00252763
      WBVar02125442
      WBVar01564430
      WBVar00252620
      WBVar01479065
      WBVar01917789
      WBVar00388720
      WBVar00388721
      WBVar00388722
      WBVar00388723
      WBVar00388724
      WBVar00388725
      WBVar02151417
      WBVar00388726
      WBVar02087837
      WBVar00388727
      WBVar00388728
      WBVar01506157
      WBVar00007021
    Strain: WBStrain00037649
    RNASeq_FPKM (74)
    GO_annotation (25)
    Ortholog (23)
    Paralog: WBGene00016754 Caenorhabditis elegans From_analysis: Panther
      WBGene00016997 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017755 Caenorhabditis elegans From_analysis: Panther
      WBGene00021552 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: zip-2 encodes a bZIP transcription factor; ZIP-2 activity is required for regulating one branch of the immune response pathway that responds to infection by virulent strains of the bacterial pathogen Pseudomonas aeruginosa; specifically, ZIP-2 is required for inducing expression of a subset of infection response genes, including irg-1 and irg-2, and for full resistance to P. aeruginosa infection. Paper_evidence: WBPaper00027309
            WBPaper00035891
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Feb 2010 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to bacterium and positive regulation of macromolecule biosynthetic process. Predicted to be located in nucleus. Expressed in pharynx. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Modifies_disease: DOID:14330
  Modifies_disease_in_annotation: WBDOannot00000499
  Molecular_info: Corresponding_CDS: K02F3.4
    Corresponding_transcript (3)
    Other_sequence (25)
    Associated_feature (16)
    Gene_product_binds (249)
    Transcription_factor: WBTranscriptionFactor000223
  Experimental_info: RNAi_result (25)
    Expr_pattern: Expr7776
      Expr10045
      Expr1020648
      Expr1038353
      Expr1153467
      Expr2018156
      Expr2036293
    Drives_construct: WBCnstr00012921
      WBCnstr00015019
      WBCnstr00015163
      WBCnstr00019915
      WBCnstr00022575
      WBCnstr00025914
    Construct_product: WBCnstr00016820
      WBCnstr00018893
      WBCnstr00018894
      WBCnstr00019915
      WBCnstr00022575
      WBCnstr00025914
    Regulate_expr_cluster: WBPaper00035891:PA_induced_zip-2_dependent
      WBPaper00035891:zip-2(RNAi)_downregulated
      WBPaper00035891:zip-2(RNAi)_upregulated
      WBPaper00053605:zip-2(RNAi)_downregulated
      WBPaper00053605:zip-2(RNAi)_upregulated
    Microarray_results (21)
    Expression_cluster (221)
    Interaction (49)
    WBProcess: WBbiopr:00000008
      WBbiopr:00000039
  Map_info: Map: III Position: -25.7689
    Positive: Positive_clone: K02F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (32)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-25.7711)
  Method: Gene