Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00006592

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00006592SMapS_parentSequenceR151
IdentityVersion2
NameCGC_namedpy-31Paper_evidenceWBPaper00024637
Sequence_nameR151.5
Molecular_nameR151.5a
R151.5a.1
CE27200
R151.5a.2
R151.5b
Other_namenas-35CGC_data_submission
toh-2Paper_evidenceWBPaper00024637
Person_evidenceWBPerson465
CELE_R151.5Accession_evidenceNDBBX284603
Public_namedpy-31
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
213 Jun 2005 09:49:17WBPerson2970Name_changeCGC_namedpy-31
Other_nametoh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdpy
AlleleWBVar01500260
WBVar00401260
WBVar00401261
WBVar00401262
WBVar00401263
WBVar00401264
WBVar00563766
WBVar00837987
WBVar00837988
WBVar00837989
WBVar00837990
WBVar00837991
WBVar00837992
WBVar00837993
WBVar00837994
WBVar00837995
WBVar00059600
WBVar00837996
WBVar00837997
WBVar00837998
WBVar00059605
WBVar00837999
WBVar00838000
WBVar00838001
WBVar01645366
WBVar00838002
WBVar00838003
WBVar00838004
WBVar00838005
WBVar00838006
WBVar00838007
WBVar00099628
WBVar00838008
WBVar00838009
WBVar00838010
WBVar00838011
WBVar00598626
WBVar00598627
WBVar00838012
WBVar00838013
WBVar00838014
WBVar00088175
WBVar00838015
WBVar00838016
WBVar00838017
WBVar00838018
WBVar00838019
WBVar00838020
WBVar00838021
WBVar00838022
WBVar00838023
WBVar00838024
WBVar00838025
WBVar00838026
WBVar00838027
WBVar01499774
WBVar01837783
WBVar01837784
WBVar01962869
WBVar00064067
WBVar01952350
WBVar00064072
WBVar00064077
WBVar01479935
WBVar00264554
WBVar00144987
WBVar02053331
WBVar01628728
WBVar01628729
WBVar01628730
WBVar01628731
WBVar01446580
WBVar01722863
WBVar01492853
WBVar01656985
WBVar01656986
WBVar01656987
WBVar01408840
WBVar00145051
WBVar00145052
Legacy_information[C.elegansII] NMK. Encodes protein with BMP-1 similarity. [LT]
StrainWBStrain00002101
WBStrain00002309
WBStrain00004667
WBStrain00004681
WBStrain00004687
WBStrain00004688
WBStrain00004691
WBStrain00004697
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (31)
Paralog (48)
Structured_descriptionConcise_descriptiondpy-31 encodes an astacin zinc-metalloprotease of the BMP-1 (bone morphogenetic protein-1)/TOLLOID family; dpy-31 activity is required for proper cuticle formation and thus for normal body morphology; in addition, dpy-31 is essential for embryonic and larval development at 25 degrees C; genetic and immunofluorescence studies suggest that DPY-31 functions as an endopeptidase that is required for processing, and ultimately proper extracellular assembly, of the SQT-3 cuticle collagen; dpy-31 is expressed in most hypodermal cells, with the exception of larval stage seam cells, throughout the life cycle with particularly strong expression seen during embryonic and larval stages; dpy-31 is also expressed in some head neurons, the amphid socket cells, rectal epithelial cells, and vulval epithelial cells in L4 larvae and adults.Paper_evidenceWBPaper00024637
WBPaper00027067
Curator_confirmedWBPerson1843
Date_last_updated08 Aug 2006 00:00:00
Automated_descriptionPredicted to enable metalloendopeptidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in extracellular region. Expressed in several structures, including amphid sheath cell; excretory duct; hypodermis; socket cell; and vulva.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR151.5a
Corresponding_CDS_historyR151.5b:wp248
Corresponding_transcriptR151.5b
R151.5a.1
R151.5a.2
Other_sequence (44)
Associated_featureWBsf659160
WBsf716743
WBsf992958
WBsf225211
Experimental_infoRNAi_resultWBRNAi00089138Inferred_automaticallyRNAi_primary
WBRNAi00061425Inferred_automaticallyRNAi_primary
WBRNAi00061415Inferred_automaticallyRNAi_primary
WBRNAi00005194Inferred_automaticallyRNAi_primary
WBRNAi00017871Inferred_automaticallyRNAi_primary
WBRNAi00051977Inferred_automaticallyRNAi_primary
WBRNAi00061424Inferred_automaticallyRNAi_primary
Expr_pattern (13)
Drives_constructWBCnstr00002877
WBCnstr00002878
WBCnstr00004447
WBCnstr00011166
WBCnstr00013625
WBCnstr00015220
WBCnstr00020247
WBCnstr00020355
WBCnstr00034283
Construct_productWBCnstr00011166
WBCnstr00013625
WBCnstr00016573
WBCnstr00034283
AntibodyWBAntibody00002061
Microarray_results (25)
Expression_cluster (177)
InteractionWBInteraction000004828
WBInteraction000005319
WBInteraction000005375
WBInteraction000052808
WBInteraction000052809
WBInteraction000579000
Map_infoMapIIIPosition-0.771
PositivePositive_cloneR151Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5431
4146
Pseudo_map_position
Reference (25)
Remark (2)
MethodGene