Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00004749

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00004749SMapS_parentSequenceF57C7
IdentityVersion1
NameCGC_namesdn-1Person_evidenceWBPerson1831
Sequence_nameF57C7.3
Molecular_nameF57C7.3a
F57C7.3a.1
CE05996
F57C7.3b
CE32681
F57C7.3b.1
Other_nameCELE_F57C7.3Accession_evidenceNDBBX284606
Public_namesdn-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsdn
AlleleWBVar01182175
WBVar01182176
WBVar01182177
WBVar01182178
WBVar01182179
WBVar01182180
WBVar01182181
WBVar01182182
WBVar01182183
WBVar01182184
WBVar01182185
WBVar01182186
WBVar02074533
WBVar01182187
WBVar01182188
WBVar01182189
WBVar01182190
WBVar01182191
WBVar00601534
WBVar01711115
WBVar02124143
WBVar01620343
WBVar00082627
WBVar00082630
WBVar00064044
WBVar00064049
WBVar00064054
WBVar02121065
WBVar01759269
WBVar01928180
WBVar02120546
WBVar01551975
WBVar00091740
WBVar01499286
WBVar00515472
WBVar00515473
WBVar00515474
WBVar00515475
WBVar00515476
WBVar00515477
WBVar00275474
WBVar00515478
WBVar00515479
WBVar00515480
WBVar00515481
WBVar01474467
WBVar01182163
WBVar01182164
WBVar01182165
WBVar01182166
WBVar01182167
WBVar01182168
WBVar01182169
WBVar01182170
WBVar01182171
WBVar01498960
WBVar01182172
WBVar01182173
WBVar01500067
WBVar01182174
StrainWBStrain00031428
WBStrain00000144
WBStrain00050774
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (42)
Structured_descriptionConcise_descriptionsdn-1 encodes a homolog of vertebrate syndecan-2, a type I transmembrane heparan sulfate proteoglycan; by homology, SDN-1 is predicted to play a role in cell-cell and cell-matrix adhesion; loss of sdn-1 activity via RNA-mediated interference (RNAi) indicates that SDN-1 is required for backward locomotion and for normal development of the egg-laying system, particularly gonadal and vulval structures; SDN-1 is expressed in a subset of neuronal cell bodies and their associated processes in the nerve ring, and also in select tail neurons.Paper_evidenceWBPaper00011289
WBPaper00018603
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionInvolved in embryo development; epidermis morphogenesis; and nematode larval development. Located in cell surface. Expressed in several structures, including neuroblasts; neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Hodgkin's lymphoma; cleft lip; and glucose metabolism disease (multiple). Is an ortholog of human SDC1 (syndecan 1); SDC2 (syndecan 2); and SDC4 (syndecan 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9296Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10659)
DOID:8567Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10658)
DOID:4195Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10658)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10658)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10659)
DOID:5844Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10661)
DOID:674Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10659)
Molecular_infoCorresponding_CDSF57C7.3a
F57C7.3b
Corresponding_CDS_historyF57C7.3:wp83
Corresponding_transcriptF57C7.3a.1
F57C7.3b.1
Other_sequence (22)
Associated_feature (27)
Experimental_infoRNAi_resultWBRNAi00109528Inferred_automaticallyRNAi_primary
WBRNAi00109334Inferred_automaticallyRNAi_primary
WBRNAi00048861Inferred_automaticallyRNAi_primary
WBRNAi00102205Inferred_automaticallyRNAi_primary
WBRNAi00109237Inferred_automaticallyRNAi_primary
WBRNAi00065732Inferred_automaticallyRNAi_primary
WBRNAi00033032Inferred_automaticallyRNAi_primary
WBRNAi00109625Inferred_automaticallyRNAi_primary
WBRNAi00109431Inferred_automaticallyRNAi_primary
Expr_pattern (12)
Drives_constructWBCnstr00000700
WBCnstr00001405
WBCnstr00001406
WBCnstr00019775
WBCnstr00020032
WBCnstr00035413
Construct_product (13)
AntibodyWBAntibody00000804
WBAntibody00002534
Microarray_results (26)
Expression_cluster (124)
Interaction (34)
Anatomy_function (3)
Map_infoMapXPosition2.31221Error0.009839
PositivePositive_cloneF57C7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4532
4652
4134
Pseudo_map_position
Reference (47)
RemarkSequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene