WormBase Tree Display for Gene: WBGene00010813

WBGene00010813 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 2
    Name: CGC_name: pitp-1 Person_evidence: WBPerson284
            WBPerson433
      Sequence_name: M01F1.7
      Molecular_name: M01F1.7
        M01F1.7.1
        CE33673
      Other_name: CELE_M01F1.7 Accession_evidence: NDB BX284603
      Public_name: pitp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Oct 2010 15:41:12 WBPerson2970 Name_change: CGC_name: pitp-1
                Sequence_name: M01F1.7
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pitp
    Allele: WBVar00531944 Inferred_automatically: From strain object: JN1209
      WBVar00531945 Inferred_automatically: From strain object: JN1297
      WBVar01262011
      WBVar01262013
      WBVar01262014
      WBVar02108273
      WBVar01500082
      WBVar02150311
      WBVar01938786
      WBVar01938787
      WBVar01541646
      WBVar00045731
      WBVar01709806
      WBVar01709807
      WBVar00045751
      WBVar00045761
      WBVar01578820
      WBVar01837356
      WBVar01578821
      WBVar01837357
      WBVar00045766
      WBVar01837358
      WBVar01837359
      WBVar01837360
      WBVar01498832
      WBVar01837361
      WBVar01837362
      WBVar01837363
      WBVar01837364
      WBVar01837365
      WBVar00250492
      WBVar01837366
      WBVar00816292
      WBVar00816293
      WBVar00816294
      WBVar00816295
      WBVar00816296
      WBVar00816297
      WBVar00816298
      WBVar00098837
      WBVar00816299
      WBVar00816300
      WBVar00562744
      WBVar00816301
      WBVar00816302
      WBVar00816303
      WBVar00816304
      WBVar00816305
      WBVar00816306
      WBVar00816307
      WBVar00816308
      WBVar00816309
      WBVar00816310
      WBVar00816311
      WBVar00816312
      WBVar00816313
      WBVar00816314
      WBVar00816315
      WBVar00816316
      WBVar00816317
      WBVar00816318
      WBVar01490031
      WBVar00816319
      WBVar01479545
      WBVar00816320
      WBVar01479546
      WBVar00816321
      WBVar01479547
      WBVar00816322
      WBVar00816323
      WBVar01408336
      WBVar00816324
      WBVar01785285
      WBVar01408337
      WBVar00816325
      WBVar01785286
      WBVar00816326
      WBVar01408338
      WBVar01408339
      WBVar00816327
      WBVar00816328
      WBVar01408340
      WBVar00816329
      WBVar00816330
      WBVar00816331
      WBVar00816332
      WBVar00816333
      WBVar02131765
      WBVar00816334
      WBVar00816335
      WBVar00816336
      WBVar00816337
      WBVar00816338
      WBVar02015136
      WBVar00056721
      WBVar01656198
      WBVar01656199
      WBVar00394215
      WBVar00394216
      WBVar01330265
      WBVar00394217
      WBVar00394218
      WBVar00394219
      WBVar00394220
      WBVar00394221
      WBVar00394222
      WBVar00394223
      WBVar00394224
      WBVar00394225
      WBVar00394226
      WBVar01994920
      WBVar00394227
      WBVar00394228
      WBVar00394229
      WBVar00394230
      WBVar01643919
      WBVar00394231
      WBVar01444988
      WBVar01444989
      WBVar02053193
      WBVar02053194
      WBVar02053195
      WBVar02053196
      WBVar02053197
    Strain: WBStrain00022698
      WBStrain00022699
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (45)
    Paralog: WBGene00022155 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021854 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: pitp-1 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); pitp-1 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; PITP-1 is predicted to mediate PIP(2) signalling in either neuronal function or cytokinesis. Paper_evidence: WBPaper00004403
            WBPaper00004651
            WBPaper00005654
            WBPaper00012751
            WBPaper00012871
            WBPaper00013030
            WBPaper00013086
            WBPaper00013591
            WBPaper00023591
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 08 Nov 2010 00:00:00
      Automated_description: Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Located in ciliary transition zone and synapse. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Is an ortholog of human PITPNM1 (phosphatidylinositol transfer protein membrane associated 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111010 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21043)
  Molecular_info: Corresponding_CDS: M01F1.7
    Corresponding_CDS_history: M01F1.7:wp98
    Corresponding_transcript: M01F1.7.1
    Other_sequence (18)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00067300 Inferred_automatically: RNAi_primary
      WBRNAi00017105 Inferred_automatically: RNAi_primary
      WBRNAi00067057 Inferred_automatically: RNAi_primary
      WBRNAi00050773 Inferred_automatically: RNAi_primary
      WBRNAi00050774 Inferred_automatically: RNAi_primary
      WBRNAi00085867 Inferred_automatically: RNAi_primary
      WBRNAi00006068 Inferred_automatically: RNAi_primary
      WBRNAi00034363 Inferred_automatically: RNAi_primary
      WBRNAi00001081 Inferred_automatically: RNAi_primary
      WBRNAi00007157 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9287
      Expr15667
      Expr1016405
      Expr1034740
      Expr1154468
      Expr2014936
      Expr2033171
    Drives_construct: WBCnstr00008579
      WBCnstr00008581
      WBCnstr00013876
      WBCnstr00031130
      WBCnstr00042468
    Construct_product: WBCnstr00008581
      WBCnstr00008585
      WBCnstr00013876
      WBCnstr00031130
    Microarray_results (19)
    Expression_cluster (143)
    Interaction: WBInteraction000006511
      WBInteraction000006754
      WBInteraction000033266
      WBInteraction000157034
      WBInteraction000161496
      WBInteraction000161504
      WBInteraction000161505
      WBInteraction000164247
      WBInteraction000164248
      WBInteraction000238852
      WBInteraction000314407
      WBInteraction000339719
      WBInteraction000343219
      WBInteraction000461410
      WBInteraction000504839
  Map_info: Map: III Position: -5.98197 Error: 0.072065
    Positive: Positive_clone: M01F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene