WormBase Tree Display for Gene: WBGene00020082

WBGene00020082 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: gcp-2.1 Person_evidence: WBPerson683
      Sequence_name: R57.1
      Molecular_name: R57.1a
        R57.1a.1
        CE30114
        R57.1b
        CE37270
        R57.1c
        CE12844
        R57.1b.1
        R57.1c.1
      Other_name: CELE_R57.1 Accession_evidence: NDB BX284606
      Public_name: gcp-2.1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Apr 2013 09:53:02 WBPerson2970 Name_change: CGC_name: gcp-2.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gcp
    Allele: WBVar02048360
      WBVar02093365
      WBVar02151246
      WBVar01617906
      WBVar01639509
      WBVar01617907
      WBVar01639510
      WBVar01617908
      WBVar01639511
      WBVar01617909
      WBVar01617910
      WBVar01617911
      WBVar01617912
      WBVar01467270
      WBVar01111799
      WBVar01111800
      WBVar01111801
      WBVar00491996
      WBVar00491997
      WBVar01111802
      WBVar01111803
      WBVar00491998
      WBVar01498638
      WBVar01111804
      WBVar00491999
      WBVar01111805
      WBVar00492000
      WBVar01111806
      WBVar00492001
      WBVar00492002
      WBVar01111807
      WBVar01111808
      WBVar00492003
      WBVar01111809
      WBVar00492004
      WBVar01111810
      WBVar00492005
      WBVar01111811
      WBVar00492006
      WBVar00492007
      WBVar01111812
      WBVar00492008
      WBVar01111813
      WBVar00492009
      WBVar01111814
      WBVar01111815
      WBVar00492010
      WBVar01111816
      WBVar01986818
      WBVar00492011
      WBVar01111817
      WBVar01986819
      WBVar01986820
      WBVar01111818
      WBVar01111819
      WBVar01111820
      WBVar01111821
      WBVar02138549
      WBVar01111822
      WBVar02138550
      WBVar01111823
      WBVar01111824
      WBVar02008951
      WBVar01111825
      WBVar01111826
      WBVar01111827
      WBVar01111828
      WBVar02123426
      WBVar01111829
      WBVar01111830
      WBVar01111831
      WBVar01111832
      WBVar01111833
      WBVar01111834
      WBVar01111835
      WBVar01111836
      WBVar01111837
      WBVar01111838
      WBVar01111839
      WBVar01111840
      WBVar01111841
      WBVar01111842
      WBVar01111843
      WBVar00074206
      WBVar01111844
      WBVar01111845
      WBVar01111846
      WBVar01111847
      WBVar01111848
      WBVar01111849
      WBVar01111850
      WBVar01111851
      WBVar01111852
      WBVar00092275
      WBVar02122719
      WBVar01600263
      WBVar01689944
      WBVar00599044
      WBVar02122173
      WBVar01992431
      WBVar01992432
      WBVar01499636
      WBVar02121672
      WBVar02121498
      WBVar01823919
      WBVar01978968
      WBVar01978969
      WBVar01495463
      WBVar01978970
    Strain: WBStrain00031761
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (46)
    Paralog: WBGene00007954 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00044121 Caenorhabditis elegans From_analysis: TreeFam
            Panther
    Structured_description: Automated_description: Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human FOLH1 (folate hydrolase 1); NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2); and NAALADL1 (N-acetylated alpha-linked acidic dipeptidase like 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:7693 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3788)
      DOID:3526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3788)
  Molecular_info: Corresponding_CDS: R57.1a
      R57.1b
      R57.1c
    Corresponding_CDS_history: R57.1a:wp98
      R57.1a:wp129
      R57.1b:wp98
      R57.1b:wp129
    Corresponding_transcript: R57.1a.1
      R57.1b.1
      R57.1c.1
    Other_sequence (51)
    Associated_feature: WBsf662403
      WBsf235252
      WBsf235253
  Experimental_info: RNAi_result: WBRNAi00052044 Inferred_automatically: RNAi_primary
      WBRNAi00017915 Inferred_automatically: RNAi_primary
      WBRNAi00034973 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010413
      Expr1038722
      Expr1155679
      Expr2011970
      Expr2030207
    Drives_construct: WBCnstr00022811
      WBCnstr00025382
    Construct_product: WBCnstr00025382
    Microarray_results (31)
    Expression_cluster: WBPaper00028802:intestine_unique
      WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00039838:LEC-6_binding_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:endoderm_unique
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050504:hrp-2(RNAi)_downregulated
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054410:set-9(rw5)_upregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:gut-microbiota_downregulated
      WBPaper00056284:ints-4(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_far_posterior
      WBPaper00061340:Intestine
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061527:172183_at-176110_at
      WBPaper00061527:dhs-28_22199-acs-14
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065043:dcap-1(tm3163)_downregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:69_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_2
      cgc4489_group_3
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025032:cluster_5
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:rde-4_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_4
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036286:Pattern_C
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038462:aging_downregulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00044535:male_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(101_min)
      [cgc6390]:Cluster_C
    Interaction (48)
  Map_info: Map: X Position: -20.1873
    Positive: Positive_clone: R57 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00049244
    WBPaper00055090
    WBPaper00066339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene