WormBase Tree Display for Gene: WBGene00013218

WBGene00013218 SMap: S_parent: Sequence: Y54G11A
  Identity: Version: 1
    Name: Sequence_name: Y54G11A.9
      Molecular_name: Y54G11A.9
        Y54G11A.9.1
        CE35683
        Y54G11A.9.2
      Other_name: CELE_Y54G11A.9 Accession_evidence: NDB BX284602
      Public_name: Y54G11A.9
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar02040984
      WBVar01499702
      WBVar02040985
      WBVar01767489
      WBVar01577306
      WBVar01319951
      WBVar01319953
      WBVar01319954
      WBVar01319955
      WBVar01498435
      WBVar01319956
      WBVar01319958
      WBVar00384900
      WBVar02123209
      WBVar01498834
      WBVar01950523
      WBVar01393655
      WBVar01393666
      WBVar00014618
      WBVar00014623
      WBVar00014628
      WBVar00247664
      WBVar00788231
      WBVar00788232
      WBVar01498941
      WBVar00788233
      WBVar00788234
      WBVar00788235
      WBVar00788236
      WBVar00788237
      WBVar01989667
      WBVar00788238
      WBVar00788239
      WBVar00788240
      WBVar01563159
      WBVar01563160
    RNASeq_FPKM (74)
    GO_annotation: 00102961
      00102962
      00102963
      00102964
      00102965
      00102966
      00120119
      00120120
    Contained_in_operon: CEOP2636
    Ortholog (33)
    Paralog: WBGene00045279 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
      WBGene00012666 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable 2 iron, 2 sulfur cluster binding activity; 4 iron, 4 sulfur cluster binding activity; and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 4. Is an ortholog of human ISCA2 (iron-sulfur cluster assembly 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080136 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19857)
  Molecular_info: Corresponding_CDS: Y54G11A.9
    Corresponding_CDS_history: Y54G11A.9:wp109
    Corresponding_transcript: Y54G11A.9.1
      Y54G11A.9.2
    Other_sequence (25)
    Associated_feature: WBsf990684
      WBsf1013828
      WBsf224264
      WBsf224265
  Experimental_info: RNAi_result: WBRNAi00024222 Inferred_automatically: RNAi_primary
      WBRNAi00024149 Inferred_automatically: RNAi_primary
      WBRNAi00023349 Inferred_automatically: RNAi_primary
      WBRNAi00020465 Inferred_automatically: RNAi_primary
      WBRNAi00057434 Inferred_automatically: RNAi_primary
      WBRNAi00023862 Inferred_automatically: RNAi_primary
      WBRNAi00037489 Inferred_automatically: RNAi_primary
      WBRNAi00020990 Inferred_automatically: RNAi_primary
      WBRNAi00062452 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020954
      Expr1160870
      Expr2007930
      Expr2026172
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033131:dapk-1_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061527:F31C3.4_6048-cutc-1_15804
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00025032:cluster_147
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00035905:FBF-1_Associated
      WBPaper00037611:RNP-8-associated
      WBPaper00040963:TA300_down
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc6390]:mixed_oogenesis-somatic
    Interaction (38)
  Map_info: Positive: Positive_clone: Y54G11A Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 22.9058
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene