WormBase Tree Display for Gene: WBGene00012621

WBGene00012621 SMap: S_parent: Sequence: Y38H6C
  Identity: Version: 1
    Name: Sequence_name: Y38H6C.8
      Molecular_name: Y38H6C.8
        Y38H6C.8.1
        CE19102
      Other_name: CELE_Y38H6C.8 Accession_evidence: NDB BX284605
      Public_name: Y38H6C.8
    DB_info: Database: AceView gene 5U987
        WormQTL gene WBGene00012621
        WormFlux gene WBGene00012621
        NDB locus_tag CELE_Y38H6C.8
        Panther gene CAEEL|WormBase=WBGene00012621|UniProtKB=Q9XX56
          family PTHR22802
        NCBI gene 189689
        RefSeq protein NM_075550.3
        TREEFAM TREEFAM_ID TF317914
        TrEMBL UniProtAcc Q9XX56
        UniProt_GCRP UniProtAcc Q9XX56
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar01499709
      WBVar02124844
      WBVar02105727
      WBVar02105728
      WBVar01599104
      WBVar01599105
      WBVar01901479
      WBVar01901480
      WBVar01755134
      WBVar01755135
      WBVar01755136
      WBVar01755137
      WBVar01755138
      WBVar01755139
      WBVar01755140
      WBVar01755141
      WBVar01755142
      WBVar01755143
      WBVar01755144
      WBVar01755145
      WBVar01755146
      WBVar01755147
      WBVar01755148
      WBVar01755149
      WBVar02124918
      WBVar01755150
      WBVar00229183
      WBVar01755151
      WBVar01755152
      WBVar01755153
      WBVar02122714
      WBVar01755154
      WBVar02119769
      WBVar01755155
      WBVar01755156
      WBVar01755157
      WBVar01755158
      WBVar01755159
      WBVar01755160
      WBVar01755161
      WBVar01755162
      WBVar01755163
      WBVar01755164
      WBVar01755165
      WBVar01755166
      WBVar01755167
      WBVar01755168
      WBVar01755169
      WBVar01820910
      WBVar01755170
      WBVar01755171
      WBVar01755172
      WBVar01755173
      WBVar01490610
      WBVar01755174
      WBVar01755175
      WBVar01755176
      WBVar01499446
      WBVar01755177
      WBVar01755178
      WBVar01500000
      WBVar01755179
      WBVar00073148
      WBVar00073149
      WBVar00073150
      WBVar00073151
      WBVar01498549
      WBVar01107484
      WBVar01107485
      WBVar01107486
      WBVar01107487
      WBVar01107488
      WBVar01107489
      WBVar01107490
      WBVar01107491
      WBVar01107492
      WBVar02121668
      WBVar01107493
      WBVar01107494
      WBVar01499299
      WBVar01107495
      WBVar01107496
      WBVar01107497
      WBVar00490455
      WBVar00490456
      WBVar00490457
      WBVar00490458
      WBVar00490459
      WBVar00490460
      WBVar00490461
      WBVar01498958
      WBVar02124642
      WBVar02118757
    RNASeq_FPKM (74)
    GO_annotation: 00104143
      00104144
      00104145
      00104146
    Ortholog (26)
    Paralog (25)
    Structured_description: Automated_description: Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and cholangiocarcinoma. Is an ortholog of human REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3G (regenerating family member 3 gamma). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:9744 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:4947 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:12894 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
  Molecular_info: Corresponding_CDS: Y38H6C.8
    Corresponding_transcript: Y38H6C.8.1
    Associated_feature (3)
  Experimental_info: RNAi_result: WBRNAi00020331 Inferred_automatically: RNAi_primary
      WBRNAi00036873 Inferred_automatically: RNAi_primary
      WBRNAi00056080 Inferred_automatically: RNAi_primary
      WBRNAi00020330 Inferred_automatically: RNAi_primary
      WBRNAi00089189 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028681
      Expr1159604
      Expr2007331
      Expr2025565
    Drives_construct: WBCnstr00029880
    Construct_product: WBCnstr00029880
    Microarray_results (18)
    Expression_cluster: WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00032528:L3_depleted
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038061:aldicarb_downregulated
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:HgCl2_20uM_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_downregulated_L2
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045861:wdr-5(ok1417)_upregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050163:let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00051137:Orsay-virus_upregulated_rde-1(ne219)
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00053909:N2_vs_CB4856_downregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_L3
      WBPaper00056284:ints-9(RNAi)_upregulated
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059490:dcr-1(m9375)_downregulated
      WBPaper00059598:HeatShock_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060886:met-2(n4256)_upregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061340:AVD
      WBPaper00061340:CEP
      WBPaper00061340:FLP
      WBPaper00061340:I5
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:fbxa-35-Y39A3A.3
      WBPaper00061651:ADF_enriched
      WBPaper00061651:ASEL_enriched
      WBPaper00061651:ASI_enriched
      WBPaper00061651:ASJ_enriched
      WBPaper00061651:ASK_enriched
      WBPaper00061651:AWA_enriched
      WBPaper00061651:AWB_enriched
      WBPaper00061651:AWC_OFF_enriched
      WBPaper00061651:AWC_ON_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_upregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00065029:cadmium_upregulated
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065746:tmc-1(rg1003)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065841:35_2
      WBPaper00065841:35_3
      WBPaper00065841:77_0
      WBPaper00065841:99_0
      WBPaper00065841:101_0
      WBPaper00065841:106_0
      WBPaper00065841:107_0
      WBPaper00066085:sin-3(tm1276)_upregulated
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_21
      cgc4489_group_22
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00034739:N2lessDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00036286:Pattern_H
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040876:mir-35_downregulated
      WBPaper00041609:hpl-1_hpl-2_upregulated
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00042548:miRISC_enriched
      WBPaper00042574:JU1580_OrsayVirus_upregulated
      WBPaper00042574:rde-1(ne219)_OrsayVirus_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00044535:male_upregulated
      WBPaper00045294:0.1uM_TBBP_downregulated
      WBPaper00045807:microcystin-LR_downregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053688:E.faecalis_upregulated
    Interaction (47)
  Map_info: Positive: Positive_clone: Y38H6C Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V 25.0063
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene