WormBase Tree Display for Variation: WBVar02154143

WBVar02154143 Evidence: Curator_confirmed: WBPerson1983
  Name: Public_name: ve578
    HGVSg: CHROMOSOME_X:g.12877412_12880115del
  Sequence_details: SMap: S_parent: Sequence: K02A4
    Flanking_sequences: ttaacacccgtatcattatcatttccatgc cccaacttccttccaccccctcaaaaagcg
    Mapping_target: K02A4
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Engineered_allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00047484
    Production_method: CRISPR_Cas9
    Status: Live
  Affects: Gene: WBGene00199301
      WBGene00001149
    Transcript: K02A4.1.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-1632
        Intron_number: 2-6/7
        Exon_number: 1-8/8
      K02A4.8 VEP_consequence: transcript_ablation
        VEP_impact: HIGH
        Exon_number: 1/1
  Remark: Whole gene deletions made by the Rougvie, Moerman, Hutter and Sternberg labs that replace the coding sequence with a [LoxP + myo-2p::GFP::unc-54 3Prime UTR + rps-27p::neoR::unc-54 3Prime UTR + LoxP] cassette.
    Allele Description:+/szT1 [lon-2(e678) umnIs61] I; bcat-1(ve578[LoxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + LoxP])/szT1 X.
  Method: Engineered_allele