WormBase Tree Display for Variation: WBVar00275207

WBVar00275207 Evidence: Paper_evidence: WBPaper00027020
  Name: Public_name: x12
    Other_name (33)
    HGVSg: CHROMOSOME_I:g.14623012C>T
  Sequence_details: SMap: S_parent: Sequence: Y105E8B
    Flanking_sequences: cagatccgcaccgtctcatccagactgaag aggtccgattcttttctgtgtagtagtctt
    Mapping_target: Y105E8B
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00027020
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00033515
      WBStrain00040918
    Laboratory: ZZ
    Status: Live
  Affects: Gene: WBGene00002978
    Transcript (20)
    Interactor: WBInteraction000052055
      WBInteraction000052056
      WBInteraction000052057
      WBInteraction000052373
      WBInteraction000052374
      WBInteraction000052375
      WBInteraction000052376
      WBInteraction000052377
      WBInteraction000518956
  Genetics: Interpolated_map_position: I 25.8116
    Mapping_data: In_2_point: 209
        213
        214
        5106
        6076
      In_multi_point: 203
        246
        577
        960
        1781
        2221
        2331
        3094
        3095
      In_pos_neg_data (15)
  Description: Phenotype: WBPhenotype:0000022 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: slightly long Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000421 Paper_evidence: WBPaper00000484
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: Twitchers survive much better than wild-type on 0.1mM levamisole. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
          grows well in 1 mM levamisole Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00000484
              Person_evidence: WBPerson261
              Curator_confirmed: WBPerson2021
                WBPerson712
        Phenotype_assay: Treatment: 0.1mM and 1mM levamisole Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000422 Paper_evidence: WBPaper00000484
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: Muscle spasms of twitchers are greatly exacerbated on 1mM levamisole compared to 0.1mM drug or regular medium. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
          mild twitcher phenotype Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: uncoordinated Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001599 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 1mM ouabain Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001852 Paper_evidence: WBPaper00035074
        Curator_confirmed: WBPerson2021
        Remark: Mutants are resistant to tribendimidine Paper_evidence: WBPaper00035074
            Curator_confirmed: WBPerson2021
  Reference: WBPaper00035074
    WBPaper00002748
    WBPaper00014049
    WBPaper00017307
    WBPaper00000484
    WBPaper00015313
    WBPaper00016080
    WBPaper00022415
  Method: Substitution_allele