WormBase Tree Display for Variation: WBVar00266521
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| WBVar00266521 | Evidence | Paper_evidence | WBPaper00003414 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | u63 | |||||||
| Other_name | CE24843:p.Glu415Lys | ||||||||
| C44B11.3.1:c.1243G>A | |||||||||
| HGVSg | CHROMOSOME_III:g.3131843C>T | ||||||||
| Sequence_details | SMap | S_parent | Sequence | C44B11 | |||||
| Flanking_sequences | gtccactggtatgttggtgaaggaatggag | aaggagaatttagtgaggctcgtgaagatt | |||||||
| Mapping_target | C44B11 | ||||||||
| Type_of_mutation | Substitution | g | a | Paper_evidence | WBPaper00003414 | ||||
| SeqStatus | Sequenced | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Laboratory | TU | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00003175 | |||||||
| Transcript | C44B11.3.1 (11) | ||||||||
| Interactor | WBInteraction000502025 | ||||||||
| WBInteraction000504762 | |||||||||
| WBInteraction000504764 | |||||||||
| Genetics | Interpolated_map_position | III | -7.53489 | ||||||
| Description | Phenotype | WBPhenotype:0000315 | Paper_evidence | WBPaper00001125 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000962 | Paper_evidence | WBPaper00038206 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Animals exhibited reduced fluorescence in GFP-expressing touch receptor neurons (TRNs). | Paper_evidence | WBPaper00038206 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Genotype | uIs22(Pmec-3::GFP) | Paper_evidence | WBPaper00038206 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0002364 | Paper_evidence | WBPaper00044649 | |||||||
| Curator_confirmed | WBPerson9270 | ||||||||
| Remark | Spontaneous axon degeneration affecting PLM, PVM, ALM, and AVM. (Figure 5C, S3G) | Paper_evidence | WBPaper00044649 | ||||||
| Curator_confirmed | WBPerson9270 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005490 | PATO:0000460 | Paper_evidence | WBPaper00044649 | ||||
| Curator_confirmed | WBPerson9270 | ||||||||
| WBbt:0004086 | PATO:0000460 | Paper_evidence | WBPaper00044649 | ||||||
| Curator_confirmed | WBPerson9270 | ||||||||
| WBbt:0005406 | PATO:0000460 | Paper_evidence | WBPaper00044649 | ||||||
| Curator_confirmed | WBPerson9270 | ||||||||
| WBbt:0003832 | PATO:0000460 | Paper_evidence | WBPaper00044649 | ||||||
| Curator_confirmed | WBPerson9270 | ||||||||
| Phenotype_not_observed | WBPhenotype:0001676 | Paper_evidence | WBPaper00001125 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Touch cell processes have normal numbers of large diameter microtubules compared to processes in control animals. | Paper_evidence | WBPaper00001125 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Reference | WBPaper00038206 | ||||||||
| WBPaper00001125 | |||||||||
| WBPaper00003414 | |||||||||
| WBPaper00044649 | |||||||||
| Method | Substitution_allele |
