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WormBase Tree Display for Interaction: WBInteraction000502025

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Name Class

WBInteraction000502025Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00003175Interactor_typeTrans_regulator
WBGene00003169Interactor_typeTrans_regulated
Expr_patternExpr3464
Variation_interactorWBVar00266521Interactor_typeTrans_regulator
Interaction_summaryA missense mutation, u63, mec-12 caused MEC-5::GFP restriction to the proximal portion of the axon. In this proximal region, the punctate pattern is normal.
Detection_methodReporter_gene[mec-5::gfp], full-length of mec-5 translational fused with GFP.
Regulation_resultPositive_regulateAnatomy_termWBbt:0006973
PaperWBPaper00024622
RemarkMicrotubules are needed for the transport of components needed to localize MEC-1 and MEC-5, but not for their positioning in puncta.