WormBase Tree Display for Variation: WBVar00088257

WBVar00088257 Evidence: Person_evidence: WBPerson508
  Name: Public_name: kn1
    Other_name: T07C4.7a.1:c.212G>A
      CE50785:p.Gly4Glu
      CE00598:p.Gly71Glu
      T07C4.7b.1:c.11G>A
    HGVSg: CHROMOSOME_III:g.10334600G>A
  Sequence_details: SMap: S_parent: Sequence: T07C4
    Flanking_sequences: ACCAGCCACAATTGACCTGGATGCTCTCCG ATTCCATAGAATCAGCGGTTGTGTAATGGC
    Mapping_target: T07C4
    Type_of_mutation: Substitution: g a Person_evidence: WBPerson508
              WBPerson3035
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00034909
      WBStrain00034917
    Laboratory: TK
    Status: Live
  Affects: Gene: WBGene00003225
    Transcript: T07C4.7b.1 (12)
      T07C4.7a.1 (12)
    Interactor (12)
  Genetics: Interpolated_map_position: III 2.34584
    Mapping_data: In_multi_point: 1752
        1753
        1754
        1755
        1756
        1757
        1824
        2407
  Description: Phenotype (24)
    Phenotype_not_observed: WBPhenotype:0000039 Paper_evidence: WBPaper00031688
        Curator_confirmed: WBPerson712
      WBPhenotype:0000460 Paper_evidence: WBPaper00031688
        Curator_confirmed: WBPerson712
      WBPhenotype:0000636 Paper_evidence: WBPaper00045008
        Curator_confirmed: WBPerson298
        Remark: no change in axon degeneration of severed GABA motor neuron axons. Paper_evidence: WBPaper00045008
            Curator_confirmed: WBPerson298
        EQ_annotations: Anatomy_term: WBbt:0006976 PATO:0000460 Paper_evidence: WBPaper00045008
                Curator_confirmed: WBPerson298
            WBbt:0006830 PATO:0000460 Paper_evidence: WBPaper00045008
                Curator_confirmed: WBPerson298
      WBPhenotype:0000686 Paper_evidence: WBPaper00040524
        Curator_confirmed: WBPerson712
        Remark: mev-1(kn1) mutants showed increased levels of mtROS when compared to wildtype worms. Paper_evidence: WBPaper00040524
            Curator_confirmed: WBPerson712
      WBPhenotype:0001871 Paper_evidence: WBPaper00040161
        Curator_confirmed: WBPerson712
        Remark: The short lived mitochondrial mutant mev-1 was found to be short-lived on 100 uM FUdR plates. Paper_evidence: WBPaper00040161
            Curator_confirmed: WBPerson712
      WBPhenotype:0001991 Paper_evidence: WBPaper00034694
        Curator_confirmed: WBPerson2857
        Remark: animals enter into hypoxia-induced reproductive and developmental diapause same as wild-type Paper_evidence: WBPaper00034694
            Curator_confirmed: WBPerson2857
  Reference (34)
  Remark: Allele sequenced by James Rand and Ellie Mathews
  Method: Substitution_allele