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WormBase Tree Display for Strain: WBStrain00007178

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Name Class

WBStrain00007178StatusLive
Genotypetlp-1(bx85) IV; him-5(e1490) V.
Public_nameEM347
ContainsGeneWBGene00001864
WBGene00006580
VariationWBVar00144039
WBVar00000593
PropertiesMutagenDiethoxybutane
CGC_received21 Oct 2002 00:00:00
LocationCGC
Made_byWBPerson1627
RemarkAlthough hermaphrodites appear WT in other ways, there are some problems with T cell lineages (affecting the phasmids) and tail cell fusions. Variably Dyf. Male tail tip morphogenesis is also defective, resulting in blobby, leptoderan tails. Males are infertile due to an inability to properly copulate. tlp-1 encodes a nuclear protein with a single C2H2-type zinc finger domain and an N-terminal SPLALLA domain, similar to that of Sp1 transcription factors of vertebrates. The bx85 mutation involves a truncation of TLP-1 due to a frameshift caused by a 5-bp deletion.Inferred_automaticallyFrom CGC strain data
ReferenceWBPaper00059342
SpeciesCaenorhabditis elegans