WormBase Tree Display for Strain: WBStrain00007178
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WBStrain00007178 | Status | Live | ||
---|---|---|---|---|
Genotype | tlp-1(bx85) IV; him-5(e1490) V. | |||
Public_name | EM347 | |||
Contains | Gene | WBGene00001864 | ||
WBGene00006580 | ||||
Variation | WBVar00144039 | |||
WBVar00000593 | ||||
Properties | Mutagen | Diethoxybutane | ||
CGC_received | 21 Oct 2002 00:00:00 | |||
Location | CGC | |||
Made_by | WBPerson1627 | |||
Remark | Although hermaphrodites appear WT in other ways, there are some problems with T cell lineages (affecting the phasmids) and tail cell fusions. Variably Dyf. Male tail tip morphogenesis is also defective, resulting in blobby, leptoderan tails. Males are infertile due to an inability to properly copulate. tlp-1 encodes a nuclear protein with a single C2H2-type zinc finger domain and an N-terminal SPLALLA domain, similar to that of Sp1 transcription factors of vertebrates. The bx85 mutation involves a truncation of TLP-1 due to a frameshift caused by a 5-bp deletion. | Inferred_automatically | From CGC strain data | |
Reference | WBPaper00059342 | |||
Species | Caenorhabditis elegans |