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WormBase Tree Display for Gene: WBGene00001864

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Name Class

WBGene00001864SMapS_parentSequenceD1086
IdentityVersion2
NameCGC_namehim-5Person_evidenceWBPerson261
Sequence_nameD1086.4
Molecular_nameD1086.4a
WP:CE09062
CE09062
D1086.4b
WP:CE45310
CE45310
Other_nameCELE_D1086.4Accession_evidenceNDBBX284605
Public_namehim-5
DB_infoDatabaseWormQTLgeneWBGene00001864
WormFluxgeneWBGene00001864
NDBlocus_tagCELE_D1086.4
NCBIgene183932
RefSeqmRNANM_001269627.1
NM_001269626.1
proteinNP_001256556.1
NP_001256555.1
TrEMBLUniProtAccO17724
E1B6V2
UniProt_GCRPUniProtAccO17724
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
222 Aug 2008 17:09:12WBPerson2970EventAcquires_mergeWBGene00008391
Name_changeSequence_nameD1086.4
Acquires_mergeWBGene00008391
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhim
Reference_alleleWBVar00144023
Allele (39)
Legacy_informatione1467ts : at 20x self-progeny 16% XO male 11% ova are nullo-X as a result of reductional meiotic nondisjunction; X chromosome recombination specifically reduced 50%. ES3 (progeny). ME3. NA2 (e1490 (stronger allele : 33% Him at 20x)).
See also e1467, e1490
[C.elegansII] e1467ts : at 20C self-progeny 16% XO male, 3% 3X herm, 11% ova are nullo-X as a result of reductional meiotic nondisjunction; X chromosome recombination specifically reduced 50% or more, except at left end (increased); additional sterility not due to autosomal nondisjunction ( brood reduced 64% at 25C); some embryonic lethality. ES3 (progeny). ME3. OA4: e1490 (stronger allele : 33% Him at 20C)). Cloned: cosmid rescue K02A12. [Hodgkin et al. 1979; Broverman and Meneely 1994; FH]
Strain (311)
RNASeq_FPKM (74)
GO_annotation00004510
00023531
00023532
00023533
Structured_descriptionProvisional_descriptionhim-5 was identified in screens for genes that when mutated resulted in an increased frequency of X chromosome nondisjunction and thus, an increased frequency of genotypically XO males in self-fertile populations; him-5 functions in X chromosome dynamics by regulating the number and distribution of X chromosome pairing events.Paper_evidenceWBPaper00000179
WBPaper00001852
Curator_confirmedWBPerson1843
Date_last_updated28 Oct 2010 00:00:00
Concise_descriptionhim-5 was identified in screens for genes that when mutated resulted in an increased frequency of X chromosome nondisjunction and thus, an increased frequency of genotypically XO males in self-fertile populations; him-5 functions in X chromosome dynamics by regulating the number and distribution of X chromosome pairing events.
Molecular_infoCorresponding_CDSD1086.4a
D1086.4b
Corresponding_transcriptD1086.4a
D1086.4b
Associated_featureWBsf647510
WBsf232867
WBsf232868
WBsf232869
Experimental_infoRNAi_resultWBRNAi00030368Inferred_automaticallyRNAi_primary
WBRNAi00012552Inferred_automaticallyRNAi_primary
WBRNAi00061770Inferred_automaticallyRNAi_primary
WBRNAi00043422Inferred_automaticallyRNAi_primary
Expr_patternExpr9917
Expr1023729
Expr1031097
Expr1147415
Drives_constructWBCnstr00036641
WBCnstr00038151
Construct_productWBCnstr00036641
WBCnstr00038150
WBCnstr00038151
Microarray_results (16)
Expression_cluster (69)
Interaction (67)
Map_infoMapVPosition6.09216Error0.018285
Well_ordered
PositivePositive_cloneD1086Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point308
6177
Multi_point (33)
Pos_neg_data1761
4301
6866
7401
Landmark_gene
Reference (205)
RemarkThis locus was previously connected to Y54G2A.1 which was a mistake [030212 krb]
MethodGene