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WormBase Tree Display for Gene: WBGene00001864

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Name Class

WBGene00001864SMapS_parentSequenceD1086
IdentityVersion2
NameCGC_namehim-5Person_evidenceWBPerson261
Sequence_nameD1086.4
Molecular_nameD1086.4a
D1086.4a.1
CE09062
D1086.4b
CE45310
D1086.4b.1
Other_nameCELE_D1086.4Accession_evidenceNDBBX284605
Public_namehim-5
DB_infoDatabaseWormQTLgeneWBGene00001864
WormFluxgeneWBGene00001864
NDBlocus_tagCELE_D1086.4
NCBIgene183932
RefSeqproteinNM_001269627.3
NM_001269626.2
TrEMBLUniProtAccO17724
E1B6V2
UniProt_GCRPUniProtAccO17724
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
222 Aug 2008 17:09:12WBPerson2970EventAcquires_mergeWBGene00008391
Name_changeSequence_nameD1086.4
Acquires_mergeWBGene00008391
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhim
Reference_alleleWBVar00144023
Allele (43)
Legacy_informatione1467ts : at 20x self-progeny 16% XO male 11% ova are nullo-X as a result of reductional meiotic nondisjunction; X chromosome recombination specifically reduced 50%. ES3 (progeny). ME3. NA2 (e1490 (stronger allele : 33% Him at 20x)).
See also e1467, e1490
[C.elegansII] e1467ts : at 20C self-progeny 16% XO male, 3% 3X herm, 11% ova are nullo-X as a result of reductional meiotic nondisjunction; X chromosome recombination specifically reduced 50% or more, except at left end (increased); additional sterility not due to autosomal nondisjunction ( brood reduced 64% at 25C); some embryonic lethality. ES3 (progeny). ME3. OA4: e1490 (stronger allele : 33% Him at 20C)). Cloned: cosmid rescue K02A12. [Hodgkin et al. 1979; Broverman and Meneely 1994; FH]
Strain (490)
RNASeq_FPKM (74)
GO_annotation00008104
00030516
00030517
00030518
OrthologchrV_pilon.g16429Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionhim-5 was identified in screens for genes that when mutated resulted in an increased frequency of X chromosome nondisjunction and thus, an increased frequency of genotypically XO males in self-fertile populations; him-5 functions in X chromosome dynamics by regulating the number and distribution of X chromosome pairing events.Paper_evidenceWBPaper00000179
WBPaper00001852
Curator_confirmedWBPerson1843
Date_last_updated28 Oct 2010 00:00:00
Automated_descriptionInvolved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination and meiotic chromosome segregation. Located in condensed chromosome. Expressed in gonad.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSD1086.4a
D1086.4b
Corresponding_transcriptD1086.4a.1
D1086.4b.1
Associated_featureWBsf647510
WBsf232867
WBsf232868
WBsf232869
Experimental_infoRNAi_resultWBRNAi00030368Inferred_automaticallyRNAi_primary
WBRNAi00111474Inferred_automaticallyRNAi_primary
WBRNAi00012552Inferred_automaticallyRNAi_primary
WBRNAi00061770Inferred_automaticallyRNAi_primary
WBRNAi00043422Inferred_automaticallyRNAi_primary
WBRNAi00111473Inferred_automaticallyRNAi_primary
Expr_patternExpr9917
Expr1023729
Expr1031097
Expr1147415
Expr2012430
Expr2030666
Drives_constructWBCnstr00036641
WBCnstr00038151
Construct_productWBCnstr00036641
WBCnstr00038150
WBCnstr00038151
Microarray_results (18)
Expression_cluster (137)
InteractionWBInteraction000052427
WBInteraction000052836
WBInteraction000135122
WBInteraction000207924
WBInteraction000229703
WBInteraction000249693
WBInteraction000254284
WBInteraction000258008
WBInteraction000275732
WBInteraction000283949
WBInteraction000299787
WBInteraction000301535
WBInteraction000305012
WBInteraction000309747
WBInteraction000310647
WBInteraction000311098
WBInteraction000312899
WBInteraction000321565
WBInteraction000326894
WBInteraction000329127
WBInteraction000331635
WBInteraction000332936
WBInteraction000333137
WBInteraction000338896
WBInteraction000339071
WBInteraction000341520
WBInteraction000347187
WBInteraction000350425
WBInteraction000351674
WBInteraction000352846
WBInteraction000353876
WBInteraction000354752
WBInteraction000354918
WBInteraction000358072
WBInteraction000359786
WBInteraction000360653
WBInteraction000362370
WBInteraction000364172
WBInteraction000367078
WBInteraction000368413
WBInteraction000377414
WBInteraction000379579
WBInteraction000379684
WBInteraction000393671
WBInteraction000394254
WBInteraction000397550
WBInteraction000402641
WBInteraction000402855
WBInteraction000403067
WBInteraction000404918
WBInteraction000415120
WBInteraction000420301
WBInteraction000423262
WBInteraction000424185
WBInteraction000434320
WBInteraction000435248
WBInteraction000436404
WBInteraction000436549
WBInteraction000444119
WBInteraction000447651
WBInteraction000447706
WBInteraction000450497
WBInteraction000452492
WBInteraction000453100
WBInteraction000461444
WBInteraction000461670
WBInteraction000501188
WBInteraction000547131
Map_infoMapVPosition6.09216Error0.018285
Well_ordered
PositivePositive_cloneD1086Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point308
6177
Multi_point (33)
Pos_neg_data1761
4301
6866
7401
Landmark_gene
Reference (239)
RemarkThis locus was previously connected to Y54G2A.1 which was a mistake [030212 krb]
MethodGene